[1] NAGELKERKE S Q, PORCELIJN L, GEISSLER J, et al. The association and functional relevance of genetic variation in low-tomedium-affinity Fc-gamma receptors with clinical platelet transfusion refractoriness[J]. J Thromb Haemost, 2020, 18(8): 2047-2053. [2] STEFELY J A, GAILEY M, KNUDSON M, et al. Retrospective cohort studies of repeat donors reveal donor-dependent variability in the recovery of transfused platelets[J]. Transfusion, 2020, 60(8): 1837-1845. [3] NURHAYATI R W, OJIMA Y, TAYA M. Recent developments in ex vivo platelet production[J]. Cytotechnology, 2016, 68(6): 2211-2221. [4] POTTS K S, SARGEANT T J, MARKHAM J F, et al. A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo[J]. Blood, 2014, 124(17): 2725-2729. [5] LEFRANÇAIS E, ORTIZ-MUÑOZ G, CAUDRILLIER A, et al. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors[J]. Nature, 2017, 544(7648): 105-109. [6] LOONEY M R. The incomparable platelet: holy alveoli![J]. Blood, 2018, 132(11): 1088-1089. [7] LOONEY M R, HEADLEY M B. Live imaging of the pulmonary immune environment[J]. Cell Immunol, 2020, 350: 103862. [8] ALVARADO L J, HUNTSMAN H D, CHENG H, et al. Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-Γ[J]. Blood, 2019, 133(19): 2043-2055. [9] ETO K. Platelets using iPS cell technology; large scale manufacturing [J]. J Stem Cells Regen Med, 2019, 15(2): 52. [10] HANSEN M, VON LINDERN M, VAN DEN AKKER E, et al. Humaninduced pluripotent stem cell-derived blood products: state of the art and future directions[J]. FEBS Lett, 2019, 593(23): 3288-3303. [11] TAKAYAMA N, NISHIMURA S, NAKAMURA S, et al. Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells[J]. J Exp Med, 2010, 207(13): 2817-2830. [12] NAKAMURA S, TAKAYAMA N, HIRATA S, et al. Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells[J]. Cell Stem Cell, 2014, 14(4): 535-548. [13] SHEPHERD J H, HOWARD D, WALLER A K, et al. Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cell-derived megakaryocytes: Enhancing production and purity[J]. Biomaterials, 2018, 182: 135-144. [14] BLUTEAU O, LANGLOIS T, RIVERA-MUNOZ P, et al. Developmental changes in human megakaryopoiesis[J]. J Thromb Haemost, 2013, 11(9): 1730-1741. [15] POTTS K S, SARGEANT T J, MARKHAM J F, et al. A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo[J]. Blood, 2014, 124(17): 2725-2729. [16] MATSUBARA Y, SAITO E, SUZUKI H, et al. Generation of megakaryocytes and platelets from human subcutaneous adipose tissues [J]. Biochem Biophys Res Commun, 2009, 378(4): 716-720. [17] MATSUBARA Y, SUZUKI H, IKEDA Y, et al. Generation of megakaryocytes and platelets from preadipocyte cell line 3T3-L1, but not the parent cell line 3T3, in vitro[J]. Biochem Biophys Res Commun, 2010, 402(4): 796-800. [18] ONO-URUGA Y, TOZAWA K, HORIUCHI T, et al. Human adipose tissue-derived stromal cells can differentiate into megakaryocytes and platelets by secreting endogenous thrombopoietin[J]. J Thromb Haemost, 2016, 14(6): 1285-1297. [19] TOZAWA K, ONO-URUGA Y, YAZAWA M, et al. Megakaryocytes and platelets from a novel human adipose tissue-derived mesenchymal stem cell line[J]. Blood, 2019, 133(7): 633-643. [20] GAUR M, KAMATA T, WANG S, et al. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function[J]. J Thromb Haemost, 2006, 4(2): 436-442. [21] TAKAYAMA N, NISHIKII H, USUI J, et al. Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGFpromoted structures that concentrate hematopoietic progenitors[J]. Blood, 2008, 111(11): 5298-5306. [22] HUANG N, LOU M, LIU H, et al. Identification of a potent small molecule capable of regulating polyploidization, megakaryocyte maturation, and platelet production[J]. J Hematol Oncol, 2016, 9(1): 136. [23] JAROCHA D, VO K K, LYDE R B, et al. Enhancing functional platelet release in vivo from in vitro-grown megakaryocytes using small molecule inhibitors[J]. Blood Adv, 2018, 2(6): 597-606. [24] SIX K R, SICOT G, DEVLOO R, et al. A comparison of haematopoietic stem cells from umbilical cord blood and peripheral blood for platelet production in a microfluidic device[J]. Vox Sang, 2019, 114(4): 330-339. [25] MARINI I, RIGONI F, ZLAMAL J, et al. Blood donor-derived buffy coat to produce platelets in vitro[J]. Vox Sang, 2020, 115(1): 94-102. [26] 索伦·斯特芬森, 格拉尔德·贝斯特, 盖伊·赫尔曼斯, 等. 结合聚集蛋白聚糖的免疫球蛋白: CN110997716A[P]. 2020-04-10. [27] 卡伦·西莱恩克. 治疗性多肽, 其同源物、 其片段及其在调节血小板介导的聚集方面的应用: CN101412759[P]. 2009-04-22. [28] 卢信彤, 关秀茹. 血小板及其替代物输注的研究进展[J]. 医学综述, 2017, 23(15): 3012-3016. [29] SANTO V E, GOMES M E, MANO J F, et al. Chitosan-chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine[J]. J Tissue Eng Regen Med, 2012, 6(Suppl 3): s47-s59. [30] LI Y, KNISS D A, LASKY L C, et al. Culturing and differentiation of murine embryonic stem cells in a three-dimensional fibrous matrix[J]. Cytotechnology, 2003, 41(1): 23-35. [31] SULLENBARGER B, BAHNG J H, GRUNER R, et al. Prolonged continuous in vitro human platelet production using three-dimensional scaffolds[J]. Exp Hematol, 2009, 37(1): 101-110. [32] DI BUDUO C A, WRAY L S, TOZZI L, et al. Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies[J]. Blood, 2015, 125(14): 2254-2264. [33] BLIN A, LE GOFF A, MAGNIEZ A, et al. Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics[J]. Sci Rep, 2016, 6: 21700. [34] ITO Y, NAKAMURA S, SUGIMOTO N, et al. Turbulence activates platelet biogenesis to enable clinical scale ex vivo production[J]. Cell, 2018, 174(3): 636-648. [35] AVANZI M P, OLUWADARA O E, CUSHING M M, et al. A novel bioreactor and culture method drives high yields of platelets from stem cells[J]. Transfusion, 2016, 56(1): 170-178. [36] BEAU MITCHELL W, AVANZI M P. Megakaryocyte and platelet production from stem cells: US9574178[P]. 2017-02-21. |