发光细菌暗变种对化合物的致突变效应的检测

doi:10.3969/j.issn.1004-616x.1999.05.018

癌变·畸变·突变 ›› 1999, Vol. 11 ›› Issue (5): 256-258.doi: 10.3969/j.issn.1004-616x.1999.05.018

发光细菌暗变种对化合物的致突变效应的检测

韩桂春1 　谢　维2 　张秀君3

1辽宁省环境监测中心站　沈阳　110031 　2 抚顺环境监测中心站　抚顺　113006 　3 沈阳大学师范学院　沈阳　110015

收稿日期:1999-07-15 修回日期:1999-09-15 出版日期:1999-09-30 发布日期:1999-09-30

THE DETECTION OF PHOTOBACTERIUM PHOSPHOREUM DARK MUTANT TO CHEMICALS’MUTAGENIC EFFECT

Han Guichun1 , Xie Wei2 , Zhang Xiujun3

1L iao Ning Envi ronmental Monitoring Center S tation , S henyang 　110031 , 2Fu S hun Envi ronmental Monitoring Center S tation , Fushun 　113006 , 3S hen Yang University Normal College , S henyang 　110015

Received:1999-07-15 Revised:1999-09-15 Online:1999-09-30 Published:1999-09-30

摘要/Abstract

摘要： 从明亮发光杆菌T3 小种( Photobacterium Phosphoreum T3 Sp) 分离到的自发暗变种( k 变种) T9171 菌株检测十种化合物,其中六种化合物呈致突变阳性反应,二种化合物呈可凝阳性,二种化合物呈阴性反应,该方法比较传统的Ames 试验检测化合物致突变效应灵敏度高,可望成为一种简易灵敏的测试环境致突变物的短期生物学试验方法。

关键词: 发光细菌, 暗变种

Abstract: The positive mutagenic response to six chemicals and doubtable positive mutagenic response to two chemicals and negative mutagenic response to two chemicals were demonst rated by a spontaneous dark mutant (kmutant) , St rain T9171 , isolated from photobacterium phosphoreum T3 Spp. Mutagenic mutant has higher sensitivity to genotoxic chemicals as compared with conventional Ames test . It is possible to become a simple sensitive short-term bioloical test method for the detection to mutagenic compounds in environment .

Key words: Photo 　bacteria, Dark mutant

韩桂春　谢　维　张秀君. 发光细菌暗变种对化合物的致突变效应的检测[J]. 癌变·畸变·突变, 1999, 11(5): 256-258.

Han Guichun , Xie Wei , Zhang Xiujun. THE DETECTION OF PHOTOBACTERIUM PHOSPHOREUM DARK MUTANT TO CHEMICALS’MUTAGENIC EFFECT[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1999, 11(5): 256-258.

发光细菌暗变种对化合物的致突变效应的检测

THE DETECTION OF PHOTOBACTERIUM PHOSPHOREUM DARK MUTANT TO CHEMICALS’MUTAGENIC EFFECT

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