Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (5): 268-272.doi: 10.3969/j.issn.1004-616x.1999.05.024

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FOLLOWING2UP OBSERVATION FOR THE CHANGE OF THE IMMUNOLOGIC FUNCTION IN 26 CASES EXPOSED TO LOW2DOSE RADIATION

Lu Yumin , Fu Baohua , Shao Zhiliang , et al   

  1. Henan Instit ute of Occupational Disease , Zhengz hou 　450052
  • Received:1999-05-06 Revised:1999-08-02 Online:1999-09-30 Published:1999-09-30

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Abstract: The content of serum IgG、IgA and IgM , T Lymphocyte t ransformlation rate , and the positive rate of CD4 、CD8 and N Kcell were performed in 26 cases exposed low2dose radiation in 1966 and in 1971. The results indicated that the content s of serum IgG、IgA and IgM in the irradiated group were not more different than thatin cont rol ( P > 0. 05) ; the positive rates of CD4 、CD8 and N K cell were significantly lower ( P < 0. 05 , P < 0.01) , the value of CD4/ CD8 was much higher ( P < 0. 01) , the lymphocyte t ransformlation rate was lower (0. 05< P < 0. 01) in irradiared group than in cont rol. It is suggested the low2dose radiation can inhibit the cellular immune responses of the irradiated persons.

Key words: Low-dose radiation, Immunological funtion, Following2up observation