沿淮河某市自来水有机提取物对小鼠的诱变性研究

doi:10.3969/j.issn.1004-616x.2002.02.013

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2002, Vol. 14 ›› Issue (2): 112-114.doi: 10.3969/j.issn.1004-616x.2002.02.013

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MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE

JIANG Cheng－mei1;ZUANG Ying1;TIAN Lei2

1. Department of Public Health, Bengbu Medical College, Bengbu 233003, China; 2. Bengbu City Sani-tation and Anti-epidemic Station, Bengbu 233000, China

Received:2001-05-23 Revised:2001-07-18 Online:2002-04-30 Published:2002-04-30
Contact: JIANG Cheng-mei

Abstract

Abstract: Purpose : To explore the mutagenicity of organic ext ract s of tap water in a certain city in mice. Methods : Each 200 L of water was collected separately from Huai river source water , water of clarifying filt ration , chlorinated tap water and reservoir’s water. After being adsorbed and concent rated , water samples were poured into mouse stomaches. Micronucleus frequency in mouse thoracic bone-marrow polychromatic erythrocyte ( PCE) and sperm deformity rate were determined. Results : Mutagenicity of some degree were determined from Huai river source water and chlorinated tap water. The order of mutagenic intensity was as follows ; chlorinated tap water > reservoir’s water > source water > water of clarifying filteration. Conclusions : The source water was contaminated by organic mutagens. After coagulation and precipitation , mutagenicity of source water decreased because some mutagenic organic chemicals could be removed. While chlorination increased mutagenicity of tap water.

Key words: water pollution, organic extract, mutagenicity, mouse

CLC Number:

R123. 3

JIANG Cheng－mei, ZUANG Ying, TIAN Lei. MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2002, 14(2): 112-114.

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MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE

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