山萸肉水提液的毒性实验

doi:10.3969/j.issn.1004-616x.2004.03.015

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (3): 175-177.doi: 10.3969/j.issn.1004-616x.2004.03.015

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Study on the Toxicity of the Water Extract from the Pulp of Cornus

ZHANG Hui-zhen，WU Yi-ming，WU Yong-jun，et al

Department of Environmental Health,College of Public Health ZhengzhouUniversity,Zhengzhou 450052，China

Received:2003-12-12 Revised:2004-02-09 Online:2004-05-30 Published:2004-05-30
Contact: WU Yi-ming

Abstract

Abstract: BACKGROUND ＆ AIM:To check the embryo toxicity, acute toxicity, and accumulation toxicity of water extract from the pulp of cornus. MATERIALAND METHODS:Acute toxicity test,accumulation toxicity test and teratogenicity test were used in this study. RESULTS: The test result showed that:LD50>10 g/kg,accumulation coeffcient K>5. There was no significant difference between the water extract from the pulp of cornus and negative control,but there was significant difference compared to positive control. CONCLUSION: The water extract has no acute toxicity,accumulation toxicity on the mice,and no embryhotoxicity on the embryo of mice.

Key words: pulp of cornus, the matter extracted by water, acute toxicity, accumulative toxicity, embryotoxicity

ZHANG Hui-zhen, WU Yi-ming, WU Yong-jun, et al. Study on the Toxicity of the Water Extract from the Pulp of Cornus[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2004, 16(3): 175-177.

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Study on the Toxicity of the Water Extract from the Pulp of Cornus

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