人免疫缺陷病毒_1 gag基因在人成熟精子中的表达

doi:10.3969/j.issn.1004-616x.2010.06.011

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2010, Vol. 22 ›› Issue (6): 455-457.doi: 10.3969/j.issn.1004-616x.2010.06.011

Previous Articles Next Articles

The expression of human immunodeficiency virus _1 gag gene in mature human spermatozoa

WANG Dian1,2, KANG Xiang-jin1, XIE Qing-dong1, HUANG Tian-hua1,

1. Research Center for Reproductive Medicine; 2. Forensic Medicine Department, Shantou University Medical College, Shantou 515041,Guangdong, China

Received:2010-09-07 Revised:2010-09-21 Online:2010-11-30 Published:2010-11-30
Contact: WANG Dian1

Abstract

Abstract: OBJECTIVE: To explore the possibility of HIV gag gene mRNA expression in mature human spermatozoa. METHODS: Plasmid containing HIV gag DNA were constructed, and then transfected into the mature human spermatozoa. After 24 h culture, HIV gag mRNA was detected by RT_PCR. RESULTS: HIV gag mRNA could be detected in transfected mature human spermatozoa. CONCLUSION: HIV gag gene could be expressed at mRNA level in mature human spermatozoa.

Key words: human immunodeficiency virus_1, mature human spermatozoa, mRNA

WANG Dian, KANG Xiang-jin, XIE Qing-dong, HUANG Tian-hua, . The expression of human immunodeficiency virus _1 gag gene in mature human spermatozoa[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(6): 455-457.

[1]	TIAN Wei, FANG Yan, WU Hantian, JI Buqiang, XIA Zhaolin. Expressions and activities of lncRNAs and mRNAs in acute myeloid leukemia [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(2): 110-115.
[2]	WAN Shuquan, WEI Lijun, WANG Fuhua, ZENG Yong. Expression of miR-200b-3p and PAK2 in chemotherapy-resistant and sensitive ovarian cancers [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(3): 216-221.
[3]	WEI Chao, ZHANG Xiao, GAO Jie. Expression of lncRNA and its prognostic value in pancreatic cancers [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(2): 119-126,132.
[4]	ZHANG Chaoning, LI Jintian, LIU Yongqi, LIN Xingyao. Expression of apoptosis-related genes in lung and kidney tissues of rats with radiation-induced bystander effects [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(1): 42-46.
[5]	AYIGULI·Hare, LU Yanrong, YISIKANDA·Abulimiti, ZHANG Jinrong. Expression of the LGR5 gene in rectal cancer in response to neoadjuvant chemoradiotherapy [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(1): 60-64,69.
[6]	LAI Yi, CHEN Jiahong, ZHANG Hang, YUE Cong, JIANG Yan, CHEN Tao. Molecular mechanisms of hepatoxicity caused by acrylamide in F344 rats [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(3): 174-178.
[7]	YAO Yujiang, XIE Ni, LIU Litao, LI Zhonghang, WAN Lili, ZHU Ting. Screening of genetic markers associated with lymph node metastasis in colorectal cancer [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(5): 332-340,346.
[8]	CHEN Jiahong, ZHANG Hang, LAI Yi, JIANG Yan, CHEN Tao. Cell proliferation-related mRNA expression and DNA methylation changes induced by trichloroethylene in the liver and kidney of B6C3F1 male mice [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(3): 211-215.
[9]	HUANG Aibo，HONG Wenxu，YE Jinbo，LIU Jianjun，XU Hua. Effects of trichloroethylene on mRNA expression of SET-associated proteins including eEF1A1，eEF1A2 and DDB1 in L-02 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(1): 64-67.
[10]	WANG Hui, LI Yu_wen, FENG Jiang-bin, LU Xue, FAN Li, CHEN De-qing, ZHAO hua, LIU Qing-jie. Changes of GDF15 mRNA level in lymphoblastoid cells induced by 60Co γ_rays [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(5): 352-355.
[11]	LIANG Jing;HUANG Pu;FU Wen-yu;XU Li-hong. Effect of Microcystin LR on the Transcription of Subunits of PP2A of FL and HL7702 [J]. , 2009, 21(6): 422-425.
[12]	XIA Xin-hui1, HE Li2, DAI Fu-hong3, ZHONG Gan-Ping3. Mechanisms of Controlling Histone Acetylation to Suppress Bladder Cancer Cell Proliferation [J]. , 2009, 21(1): 15-020.
[13]	WANG Qi,GUAN Jie,LUO Xiao_qing, WANG Ya_xian. The Effects of GFW on the Apoptosis of Tumor Cells in Mice [J]. , 2007, 19(5): 374-376.
[14]	WEI Yan-hong, LI Long, CAO Yu-guang, SHI Nian, DAI Zhong-hua. Expression of Heme Oxygenase-1 in Renal Cortex of Rats Acutely Poisoned by Cadmium [J]. , 2007, 19(2): 133-135.
[15]	ZHENG Jie1,ZHOU Feng-hua1,ZHANG Wei-ming2,LIU Wen-tian2. Ribosomal Protein S24 Gene Differential Expression in Gastric Cancer and Its Premalignant Lesions [J]. , 2006, 18(4): 306-309.

The expression of human immunodeficiency virus _1 gag gene in mature human spermatozoa

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments