遗传毒性基因突变评价方法的研究进展

doi:10.3969/j.issn.1004-616x.2019.05.013

[1] MORGAN T H. Chromosomes and heredity[J]. Am Nat, 1910, 44(524):449-496.
[2] 国家药品监督管理局药品审评中心. 药物遗传毒性研究技术指导原则[S/OL]. (2019-05-05). http://www.cde.org.cn/zdyz.do?method=largePage&id=298.
[3] SIERRA L M, GAIVAO I. Genotoxicity and DNA repair[M]. New York:Springer, 2014:3-22.
[4] 许雷鸣, 胡燕平, 武谷, 等. 现行药物、保健食品和化妆品Ames试验方法的比较分析[J]. 安徽医药, 2013, 17(9):1595-1597.
[5] 于仲波, 吴南翔, 金锋, 等. 1485种化学物致突变试验和致癌试验结果一致性比较[J]. 毒理学杂志, 2007, 21(4):320-321.
[6] CASSANO A, RAITANO G, MOMBELLI E, et al. Evaluation of QSAR models for the prediction of ames genotoxicity:a retrospective exercise on the chemical substances registered under the EU REACH regulation[J]. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev, 2014, 32(3):273-298.
[7] 文海若, 邵安良, 陈亮, 等. 适合纳米材料遗传毒性评价方法的选择[J]. 癌变·畸变·突变, 2018, 30(4):326-331.
[8] DOAK S H, MANSHIAN B, JENKINS G J, et al. In vitro genotoxicity testing strategy for nanomaterials and the adaptation of current OECD guidelines[J]. Mutat Res, 2012, 745(1/2):104-111.
[9] 马茂才, 黄萍, 晏辉, 等. 纳米二氧化钛和纳米氧化锌的Ames试验[J]. 癌变·畸变·突变, 2010, 22(4):302-304.
[10] JOMINI S, LABILLE J, BAUDA P, et al. Modifications of the bacterial reverse mutation test reveals mutagenicity of TiO(2) nanoparticles and byproducts from a sunscreen TiO(2)-based nanocomposite[J]. Toxicol Lett, 2012, 215(1):54-61.
[11] 许春花, 张秀萍, 许雪萍, 等. Mini-Ames与Ames实验结果一致性比较[C]//2016年第六届全国药物毒理学年会论文集(重庆), 2016:262-263.
[12] ZWART N, LAMOREE M H, HOUTMAN C J, et al. Development of a luminescent mutagenicity test for high-throughput screening of aquatic samples[J]. Toxicol In Vitro, 2018, 46:350-360.
[13] 刘波, 邓中平. tk基因突变的分子机制研究[J]. 癌变·畸变·突变, 2005, 17(3):190-192.
[14] 徐斌. 马兜铃酸诱导小鼠淋巴瘤细胞tk基因突变的研究[D]. 上海:上海交通大学, 2006.
[15] KIRKLAND D, REEVE L, GATEHOUSE D, et al. A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins[J]. Mutat Res, 2011, 721(1):27-73.
[16] MOORE M M, HARRINGTON-BROCK K, DOERR C L, et al. Differential mutant quantitation at the mouse lymphoma tk and CHO hgprt loci[J]. Mutagenesis, 1989, 4(5):394-403.
[17] 张勇. TK6和TK6-E6细胞TK、HPRT基因突变实验比较研究[D]. 成都:四川大学营养与食品卫生学, 2004.
[18] LIBER H L, YANDELL D W, LITTLE J B. A comparison of mutation induction at the tk and hprt loci in human lymphoblastoid cells;quantitative differences are due to an additional class of mutations at the autosomal tk locus[J]. Mutat Res, 1989, 216(1):9-17.
[19] PERUZZI B, ARATEN D J, NOTARO R, et al. The use of PIG-A as a sentinel gene for the study of the somatic mutation rate and of mutagenic agents in vivo[J]. Mutat Res, 2010, 705(1):3-10.
[20] KAWAGOE K, TAKEDA J, ENDO Y, et al. Molecular cloning of murine Pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus[J]. Genomics, 1994, 23(3):566-574.
[21] PARKER M W, VAN DER GOOT F G, BUCKLEY J T. Aerolysin——the ins and outs of a model channel-forming toxin[J]. Mol Microbiol, 1996, 19(2):205-212.
[22] DERTINGER S D, PHONETHEPSWATH S, WELLER P, et al. Interlaboratory Pig-a gene mutation assay trial:Studies of 1, 3-propane sultone with immunomagnetic enrichment of mutant erythrocytes[J]. Environ Mol Mutagen, 2011, 52(9):748-755
[23] GOLLAPUDI B B, LYNCH A M, HEFLICH R H, et al. The in vivo Pig-a assay:A report of the international workshop on genotoxicity testing (IWGT) work group[J]. Mutat Res Genet Toxicol Environ Mutagen, 2015, 783:23-35.
[24] BHALLI J A, DING W, SHADDOCK J G, et al. Evaluating the weak in vivo micronucleus response of a genotoxic carcinogen, aristolochic acids[J]. Mutat Res, 2013, 753(2):82-92.
[25] DERTINGER S D, PHONETHEPSWATH S, AVLASEVICH S L, et al. Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage:summary of 7 published studies and results from 11 new reference compounds[J]. Toxicol Sci, 2012, 130(2):328-348.
[26] CAO Y, YANG L, FENG N, et al. A population study using the human erythrocyte PIG-A assay[J]. Environ Mol Mutagen, 2016, 57(8):605-614.
[27] DAVID R, TALBOT E, ALLEN B, et al. The development of an in vitro Pig-a assay in L5178Y cells[J]. Arch Toxicol, 2018, 92(4):1609-1623.
[28] KRUGER C T, FISCHER B M, ARMANT O, et al. The in vitro PIG-A gene mutation assay:glycosylphosphatidylinositol (GPI)-related genotype-to-phenotype relationship in TK6 cells[J]. Arch Toxicol, 2016, 90(7):1729-1736.
[29] SEGA G A. A review of the genetic effects of ethyl methanesulfonate[J]. Mutat Res, 1984, 134(2):113-142.
[30] NOHMI T, SUZUKI T, MASUMURA K I. Recent advances in the protocols of transgenic mouse mutation assays[J]. Mutat Res, 2000, 455(1):191-215.
[31] XING G, QI X, CHEN M, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid Ⅱ in the gpt delta transgenic mouse kidney[J]. Mutat Res, 2012, 743(1/2):52-58.
[32] BEYERLE A, LONG A S, WHITR P A, et al. Poly(ethylene imine) nanocarriers do not induce mutations nor oxidative DNA damage in vitro in MutaMouse FE1 cells[J]. Mol Pharm, 2011, 8(3):976-981.

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	YANG Yu, HUANG Yali, LIN Fei, TANG Long. Acute toxicity and genotoxicity of antitumor serum thymic factor 9 peptide [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(1): 57-61.
[2]	PENG Changfeng, XIE Xing, KE Yuebin. DNA oxidation and methylation effects in nano-graphene oxide-exposed 16HBE cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 454-458,463.
[3]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 492-497.
[4]	LI Ying, CHEN Xiaming, LI Hanrong, LUO Te. Genotoxicity of three kinds of electric mosquito repellents on plant root tip cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(5): 401-405,411.
[5]	LI Ruowan, ZHOU Changhui, HUANG Pengcheng, CHANG Yan. Establishment of an in vitro PIG-A gene mutation assay based on TK6 cells for genotoxicity tests [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(3): 242-248.
[6]	ZHAO Kangtao, WANG Qinghong, LIN Jian. Teratogenic investigation of a silicon adsorbent for cold turbidity of beer on SD rats [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(5): 400-402,406.
[7]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(4): 315-317,325.
[8]	HUANG Pengcheng, ZHOU Changhui, LI Shenning, CHANG Yan. Establishment of detection method for histone γ-H2AX phosphorylation based on flow cytometry [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2017, 29(4): 284-288.
[9]	YUAN Ye, CHEN Dandan, JING Shufang, YU Yongsheng, CHEN Jianheng, WU Chunqi, SHI Chang. Mutagenic effects of N-(n-butyl)-thiophosphorictriamide in somatic and germ cells of mice [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(6): 432-437.
[10]	XU Yu, ZHANG Xiaohong, BAN Yuanyuan, FENG Qin, ZHANG Xue, CHANG Xiling, GAO Qichao. The effect of Chlorpyrifos on the growth of Drosophila melanogaster [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(6): 477-480.
[11]	YANG Hong, WU Qiuyun, LAO Canshan, LI Mingyue, LI Wenchao. DNA-damage in RAW264.7 cells exposed to different sizes of silica nanoparticles [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(4): 249-254.
[12]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(3): 243-245,249.
[13]	LU Yao, LIU Xinxia, XING Xiumei, ZHAO Zhiqiang, OU Xiaoyan, SU Xiaolin, SUN Yi, CHEN Jingli, SHEN Biling, JIANG Jun, HE Yun. DNA damage and telomere length changes in peripheral leukocytes from lead exposed workers [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(3): 179-184.
[14]	LIU Tiantian, SHEN Chunlin, LÜ Lulu, ZHANG Tianbao. Genotoxicity of PAMAM dendrimer (ethylenediamine core) generation 5.0 solution [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(5): 378-382.
[15]	WANG Ying, PU Jiang, QI Naisong, WEN Hairuo, WANG Xin, HU Yanping, SONG Jie, ZHANG Joe, WANG Xue. A high-throughput screening method and application of cell transformation assay in Bhas 42 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(4): 288-293.