Abstract: OBJECTIVE：To analyze the incidence and mortality of malignant tumors and their epidemic characteristics in the Hulunbuir in 2019. METHODS：Data from 6 registries were qualified after assessment and accepted as pooled data for final analysis. From the collected data，the incidence rate，mortality rate，age-standardized rate by Chinese standard population of incidence/mortality，age-standardized rate by world standard population of incidence/mortality，the cumulative rate of 0-74 years old and the sequence of incidence/mortality of malignant tumors were calculated. RESULTS：In 2019，the crude incidence rate was 2.888 8×10^-3，ASR China of incidence was 1.687 1×10^-3，ASR world of incidence was 1.675 1×10^-3，and the cumulative incidence rate (0-74 years old) was 18.83%. The top five cancers with high incidence were lung，colorectal，liver，breast and stomach cancers. The mortality rate was 1.915 8×10^-3，the ASR China of mortality was 1.085 7×10^-3，the ASR world of mortality was 1.096 1×10^-3，and the cumulative mortality rate (0-74 years old) was 12.41%. The top five cancers with high mortality were lung，liver，colorectal，stomach and esophageal cancers. CONCLUSION：Lung cancer，colorectal cancer，liver cancer，breast cancer，and stomach cancer pose a great threat to the health of residents in Hulunbuir and are the focus of the city's cancer prevention and treament work.

Key words: malignant tumors, incidence rate, mortality rate, sequence of incidence, sequence of mortality