[1] van der Bruggen P,Traversari C,Chomez P,et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma[J]. Science,1991,254 (5038):1643-1647. [2] Chomez P,De Backer O,Bertrand M,et al. An overview of the MAGE gene family with the identification of all human members of the family[J]. Cancer Res,2001,61 (14):5544-5551. [3] Barker PA,Salehi A. The MAGE proteins:emerging roles in cell cycle progression,apoptosis,and neurogenetic disease[J]. J Neurosci Res, 2002,67 (6):705-712. [4] Brasseur F,Rimoldi D,Liénard D,et al. Expression of MAGE genes in primary and metastatic cutaneous melanoma[J]. Int J Cancer,1995, 63 (3):375-380. [5] Jang SJ,Soria JC,Wang L,et al. Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis[J]. Cancer Res, 2001,61 (21):7959-7963. [6] Otte M,Zafrakas M,Riethdorf L,et al. MAGE-A gene expression pattern in primary breast cancer[J]. Cancer Res,2001,61 (18): 6682-6687. [7] Lin J,Lin L,Thomas DG,et al. Melanomaassociated antigens in esophageal adenocarcinoma:identification of novel MAGE-A10 splice variants[J]. Clin Cancer Res,2004,10 (17):5708-5716. [8] Bergeron A,Picard V,LaRue H,et al. High frequency of MAGE-A4 and MAGE-A9 expression in high-risk bladder cancer[J]. Int J Cancer,2009,125 (6):1365-1371. [9] Suyama T,Ohashi H,Nagai H,et al. The MAGE-A1 gene expression is not determined solely by methylation status of the promoter region in hematological malignancies[J]. Leuk Res,2002,26 (12):1113-1118. [10] Sang M,Wang L,Ding C,et al. Melanoma-associated antigen genes-an update[J]. Cancer Lett,2011,302 (2):85-90. [11] DeSmet C,Lurquin C,Lethe B,et al. DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter[J]. Mol. Cell Biol,1999,19 (11):7327-7335. [12] James SR,Link PA,Karpf AR. Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b[J]. Oncogene, 2006,25 (52):6975-6985. [13] Gaudet F,Hodgson JG,Eden A,et al. Induction of tumors in mice by genomic hypomethylation[J]. Science,2003,300 (5618):489-492. [14] Nakanish IM,Ozak IT,Yamamoto H,et al. NFBD 1 /MDC 1 associa tes with p53 and regulates its function at the cross road between cell survival and death in response to DNA damage [J]. J Boil Chem, 2007, 282 (31):22993-23004. [15] Irwin MS,Kaelin WG. p53 family update:p73 and p63 develop their own identities [J]. Cell Growth Differ,2001,12 (7):337-349. [16] Laurenz IVD,CoStanzo A,Barcarol ID,et al. Two new p73 splice variants,gamma and delta,with different transcriptional activity [J]. J Exp Med,1998,188 (9):1763-1768. [17] Monte M,Simonatto M,Peche LY,et al. MAGE-a tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents[J]. Proc Natl Acad Sci USA,2006,103 (30):11160-11165. [18] Sakurai T,Itoh K,Higashitsuji H,et al. A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells[J]. J Biol Chem, 2004,279 (15):15505-15514. [19] Peche LY,Scolz M,Ladelfa MF,et al. MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs[J]. Cell Death Differ,2012,19 (6):926-936. [20] Yang B,O’Herrin SM,Wu J,et al. MAGE-A,mMAGE-B,and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines[J]. Cancer Res, 2007, 67 (20):9954-9962. [21] Wang C,Ivanov A,Chen L,et al. MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation[J]. Embo J,2005,24 (18):3279-3290. [22] Wang C,Rauscher FJ,Cress WD,et al. Regulation of E2F1 function by the nuclear corepressor KAP1[J]. J Biol Chem,2007,282 (41): 29902-29909. [23] Doyle JM,Gao J,Wang J,et al. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases[J]. Mol Cell,2010,39 (6):963-974. [24] Marcar L,Maclaine NJ,Hupp TR,et al. MAGE-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin[J]. Cancer Res,2010,70 (24):10362-10370. [25] Ladelfa MF,Peche LY,Toledo MF,et al. Tumor-specific MAGE proteins as regulators of p53 function[J]. Cancer Letter,2012,325 (1):11-17. [26] Taniura H,Matsumoto K,Yoshikawa K. Physical and functional interactions of neuronal growth suppressor necdin with p53[J]. J Biol Chem,1999,274 (23):16242-16248. [27] Taniura H,Taniguchi N,Hara M,et al. NECDIN,a postmitotic neuron-specific growth suppressor,interacts with viral transforming proteins and cellular transcription factor E2F1[J]. J Biol Chem,1998, 273 (2):720-728. [28] Ellis L,Pan Y,Smyth GK,et al. Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma[J]. Clin Cancer Res,2008,14 (14):4500-4510. [29] Joseph J,Mudduluru G,Antony S,et al. Expression profiling of sodium butyrate (NaB)-treated cells:identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB[J]. Oncogene,2004,23 (37):6304-6315. |