癌变·畸变·突变 ›› 2001, Vol. 13 ›› Issue (3): 172-173.doi: 10.3969/j.issn.1004-616x.2001.03.012

• 论著 • 上一篇    下一篇

7 种农药对植物及人外周淋巴细胞SCE影响的比较观察

邢万金1, 王宇一2   

  1. 11 内蒙古医学院生物教研室, 内蒙 呼和浩特 010059; 2. 内蒙古医学院组胚教研室, 内蒙 呼和浩特 010059
  • 收稿日期:2000-06-27 修回日期:2000-10-18 出版日期:2001-07-30 发布日期:2001-07-30

EFFECT OF SEVEN PESTICIDES ON SISTER2CHROMATID EXCHANGE FREQUENCY OF HUMAN LYMPHOCYTES AND PLANT ROOT TIP CELLS

XING Wan-jin1, WANG Yu-yi2   

  1. 1. Department of Biology, 2. Department of Histology and Embryology, Inner Mongolia Medical College, Hohhot  010059, China
  • Received:2000-06-27 Revised:2000-10-18 Online:2001-07-30 Published:2001-07-30

摘要: 目的:研究杀虫磺、杀虫双、杀虫环、杀菌剂NF133、蚓哚乙酸、久效磷和氧化乐果7 种农药对人和植物细胞染色体的诱变性,并比较其诱变作用在人和植物上是否一致。方法:测定蚕豆、大麦根尖细胞和人外周血淋巴细胞姐妹染色单体交换(SCE)率。结果:7 种农药都能明显诱导蚕豆、大麦根尖细胞和人外周血淋巴细胞的SCE 率增加。结论:本研究中7 种农药对植物和人细胞均有较强的作用。对植物细胞与对人细胞的诱变作用是一致的。

关键词: 姐妹染色单体交换, 农药, 植物, 人外周血淋巴细胞

Abstract: Purpose : To investigate the mutagenic effect s of seven pesticides on human and plant chromosomes ,and compare their SCE2inducing effect s in human lymphocytes with those in plant root tip cells. Methods : Sister-chromatid exchange ( SCE) f reqency was determined in human lymphocytes and plant root tip cells after treatment s with pesticides. Results : Seven pesticides all induced a does2dependent increase of SCE in plant root tip cells and in human lymphocytes. Conclusion : The pesticides have st rong mutagenic effect s to human and plant chromosomes and have the same efficency in human lymphocytes and plant root tip cells.

Key words: Sister2chromatid exchange (SCE), pesticide, plant, human lymphocyte

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