癌变·畸变·突变 ›› 2007, Vol. 19 ›› Issue (6): 494-496.doi: 10.3969/j.issn.1004-616x.2007.06.018

• 论著 • 上一篇    下一篇

不同强度的低功率微波辐射对雄性小鼠生殖系统的影响

林孟端/ 陈 昱/ 陈 华/ 王修景   

  1. 福建医科大学公共卫生学院职业与环境卫生学教研室,福建 福州 350004
  • 收稿日期:2006-11-06 修回日期:2007-06-04 出版日期:2007-11-30 发布日期:2007-11-30
  • 通讯作者: 陈 华

Effects of Different Intensity of Low Power Microwave on the Reproductive System of Male Mice

LIN Meng-duan, CHEN Yu, CHEN Hua, WANG Xiu-jin   

  1. Department of Occupational and Environmental Hygiene,School of Public Health,Fujian Medical University,Fuzhou 350004,Fujian,China
  • Received:2006-11-06 Revised:2007-06-04 Online:2007-11-30 Published:2007-11-30
  • Contact: CHEN Hua

摘要: 背景与目的: 探讨不同强度低功率微波辐射对雄性小鼠生殖系统的影响。 材料与方法: 48只雄性ICR小鼠,随机分为3个辐射组和1个对照组,每组各12只,辐射组用频率900 MHz,功率密度分别为250、150、50 μW/cm2的连续波,对小鼠每天辐射24 h,连续辐射34.5 d。辐射结束观察小鼠性行为能力的扑捉潜伏期(capture incubation period ,CIP)、睾体比、睾丸病理变化、精子相对计数、精子畸形率及血清睾酮等指标的变化。 结果: 各辐射组与对照组比较, 150 μW/cm2组小鼠CIP明显延长(P<0.05)、睾丸发生轻微病理变化、精子相对计数明显减少(P<0.05);精子畸形率明显增加(P<0.05);血清睾酮水平明显降低(P<0.05);睾体比之间的差异无统计学意义。结论: 低功率微波辐射(150 μW/cm2)能引起雄性小鼠睾丸病理改变,性功能(CIP)减退,精子相对计数减少,精子畸形率升高,血清睾酮水平降低,影响雄性小鼠生殖功能。

关键词: 低功率微波, 雄性, 辐射损伤, 生殖功能

Abstract: BACKGROUND & AIM: To explore the effects of different intensities of low power microwave on the male reproductive system in mice. MATERIALS AND METHODS: 48 adult male mice were randomized into 3 microwave groups and 1 control group,each with 12 animals: microwave groups was exposed to 900 MHz microwave (250 μW/cm2, 150 μW/cm2, 50 μW/cm2,24 h/d for 34.5 d) and control group was not exposed to microwave. The sexual function: capture incubation period (CIP), the pathomorphological changes of the testes ,testis-weight ratio, comparative sperm count, malformed sperm ratio and serum testosterone were used to assess the effects of the low power microwave. RESULTS:In microwave group exposure(150 μW/cm2)testis showed slight pathological changes,comparative sperm count,serum testosterone level were significantly decreased compared with the normal control(P<0.05, respectively). CIP ,sperm malformed ratio in microwave group were significantly increased compared with the normal control group (P<0.05, respectively) .But testis-weight ratio showed no significant difference compared with the control(P>0.05, respectively). CONCLUSION: Low power microwave exposure (150 μW/cm2)could weaken sexual function(CIP) and induce pathological changes of testis, obvious increase of sperm malformed ratio , significant decrease of comparative sperm count and serum testosterone in mice.

Key words: low power microwave, maleness, radiation injury, reproductive function

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