21 种中草药抗Trp-P-1 的致突变活性

doi:10.3969/j.issn.1004-616x.1999.04.012

Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (4): 198-201.doi: 10.3969/j.issn.1004-616x.1999.04.012

Previous Articles Next Articles

ANTIMUTAGENIC ACTIVITY ON THE TRP-P-1 OF 21 CHINESE MEDICINAL PLANTS

Wu Afu1 , Wu Min1 , Wang Xue lang2 , Chen Yufeng3 , Zhu J ianer3 , MIKINIIKAWA4

1School of Pharmacy , Zhe jiang Medical University , Hangz hou 310031 , 2Department of Pharmacy , Zhejiang Pan an People’s Hospital , 　Panan 322300 , 3 S hanghai Instit ute of Materia Medicine , S hanghai 　200032 , 4 Departmant of Public Heal th , Medicinal Plants Gifu , Pharmaceutical University , Gifu 502 ,Japan

Received:1998-10-10 Revised:1999-04-14 Online:1999-07-30 Published:1999-07-30

Abstract

Abstract: The antimutagenicity of 21 t raditional Chinese herbal medicinal plant s on Trp2P21 were investigated with Ames bioassay system. It was found that Actinidia val vata Dunn , Dioscorea bulbif f era L . , A ristolochia manushuriensis Kom . , Selaginell adoederleinii Hieron . , Scutellaria rev ularis Wall . , Acanthopanax gracil2 i2styl us W . W . S mith. and Zanthox yl um bungeanum Maxim . possessed st rong antimutagenic effect s. The antimutagenic activity on the Trp2P21 of 60 % EtOH ext ract s f rom Cythula of f cinalis kuan . Curcuma Zedoaria ( Berg) . Rose had not been found but antimutagenic effect s of the aqueous ext ract s f rom Cythula of f icinalis kuan and Curcuma zedoaria ( Berg. ) Rose. on the Trp2P21 were observed.

Key words: Antimutagenicity, Chinese herbal medicines, Ames assay

Wu Afu , Wu Min , Wang Xue lang , Chen Yufeng , Zhu J ianer , MIKINIIKAWA. ANTIMUTAGENIC ACTIVITY ON THE TRP-P-1 OF 21 CHINESE MEDICINAL PLANTS[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1999, 11(4): 198-201.

[1]	SHANG Ping-ping，LI Xiang，NIE Cong，SUN Xue-hui，PENG Bin，ZHAO Le. Ames assay of native whole cigarette smoke [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2013, 25(3): 227-231.
[2]	WEI Xian-fei, TANG Rong-lan, GAN Yun-sheng, LUO Feng-jiao. The Toxicity Attenuation and Antimutagenic Effect of Health- preserving Cigarettes Made From Chinese Herbal Medicine [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2007, 19(1): 70-072.
[3]	HE Xiao-qiong, CHEN Yan-hong, XIONG Xiang-ling. Inhibitory Effect of AMH Extracted from Fungi Plant Tricholoma Matsutake on the Mutagenicity of Cigarette Smoke Condensate in vitro [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2004, 16(1): 46-49.
[4]	DENG Li-xia, Hu Bin, CHEN Xiao-jun, CHEN Tie-jiang, GUN De-xiu, ZHENG Lü-quan. STUDY OF THE GERMINATION ACTIVATED GANODERMA SPORES ON TERATOGENICITY , MUTAGENICITY AND ANTIMUTAGENICITY [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2002, 14(3): 183-185.
[5]	GUO Wei, ZHAO Ze-zhen, SHAN Bao-en, WEI Li-zhen, WEN Deng-gui. REPORT ON THE ANTIMUTAGENICITY AND ANTI2TUMOR ACTIVITY OF SIX KINDS OF CHINESE MEDICINAL HERBS [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2002, 14(2): 94-097.
[6]	YANG Sheng - li, HAN Shao - yin, ZHANG Qiao, DING Lan - ping, SONG Ai - yun, GONG Ya - ou, ZHANG Tan - mu. STUDY ON THE ANTIMUTAGENICTTY OF ORIDONIN [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2001, 13(1): 8-009.
[7]	ZHAO Ze - zhen , WEI Li - Zhen. THE REPORT ON THE MUTAGENICITY AND ANTIMUTAGENICITY SYNCHRONOUS TEST OF A LOT OF EDIBLE CHINESE HERB [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2000, 12(2): 87-089.
[8]	CHEN Guan-min , LIN Sheng-qing , HUANG Zong-xiu , CHEN Ren-xiong , HE Ling , JIANG Rui-chai. STUDY ON THE ANTIMUTAGENICITY OF LENTINAN [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2000, 12(2): 105-107.
[9]	WU Jin-long , WANG Li-yun. STUDY ON INVITRO ANTIMUTAGENICITY OF ETHANOL EXTRACT OF SCORPION [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2000, 12(1): 23-027.
[10]	Xu Xincheng , Yang Shouzhi , Peng Yiliang. INHIBITORY EFFECT OF THE COMPOUNDS EXTRACTED FROM CHINESE ALOE AND GARLICON MICRONUCLEUS RATE INDUCED BY CP AND CSC [J]. , 1999, 11(5): 233-236.
[11]	Yin Xuejun , Xiang Rende , Liu Dexiang , Zhang Xinyong , Xu Yonghua , Han Ying , Wang Rui , Wang Hechuan. A STUDY ON THE ANTIMUTAGENICITY OF CHEMICAL COMPOUNDS EXTRACTED FROM CNIDIUM MONNI ERI ( L) CUSS USED IN CHINESE TRADITIONAL MEDICINE [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1999, 11(2): 65-071.
[12]	Zhong Jinyi, Zhang yanbin, Sun Fengyun. STUDY ON THE ANTIMUTAGENICITY OF A - CM MARINE BIOLOGICAL PREPERATION [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1999, 11(1): 32-034.
[13]	Zhao Zezhen ,Wen Denggui ,Wei Lizhen and Zhi Huiying. EXPERIMENT DESIGNING FOR RAPID ASSESSMENT OF THE ROLE OF AN ANTIMUTAGEN [J]. , 1998, 10(3): 187-189.
[14]	Lan J inggang , Hu Hong , Kang Gefei. INHIBITORY EFFECT OF BIFIDOBACTERIUM BFIFIDUM AND ITS SURFACE MOLECULES ON DNA DAMAGE IN MURINE COLON MUCOSA BY MNNG [J]. , 1998, 10(1): 18-022.
[15]	Lan Jinggang , Hu Hong , Kang Gefei. INHIBITORY EFFECT OF BIFIDOBACTERIUM BIFIDUM AND ITS SURFACE MOLECULES ON THE SOS REACTION INDUCED BY MNNG [J]. , 1998, 10(1): 22-027.

ANTIMUTAGENIC ACTIVITY ON THE TRP-P-1 OF 21 CHINESE MEDICINAL PLANTS

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments