Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (2): 89-091.doi: 10.3969/j.issn.1004-616x.1999.02.008

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EFFECT OF VITAMIN E ON TOXICITY OF SALAD OIL VAPOR CONDENSATE IN MICE

Zhou Chunxian , Wang Bangxia , Xiao Di   

  1. Department of Public Heal th , Bengbu Medical College , Bengbu  233003
  • Received:1998-07-20 Revised:1998-10-21 Online:1999-03-30 Published:1999-03-30

Abstract: The effect of vitamin E (Vit E) on the rate of micronucleus and of sperm deformity in mice were observed with the micronucleus test and the sperm deformity analysis. The experimental data were calculated by statistical U test . The result s showed the rate of micronucleus and of sperm deformity of mice t reated with salad oil vapor condensate at 5ml/ kg and 10ml/ kg groups were abviously higher than that at 2. 5ml/ kg and cont rol groups ( P < 0. 01) . After the mice were supplied Vit E at 20 mg/ kg , the rate of micronucleus and of sperm deformity were significantly lower than that of salad oil vapor condensate group ( P < 0. 01) . The inhibitory effect of Vit E on the toxicity of salad oil vapor condensate was significant in mice.

Key words: Vitamin E, Salad oil vapor condensate, Toxicity effects, Mice