Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (6): 347-348.doi: 10.3969/j.issn.1004-616x.2004.06.009

Previous Articles     Next Articles

Preliminary Study on Antioxidative and Antitumor Effect of Curcuma Longa L Fluid on H22 Tumorigenic Mouse

CHEN Hua, WANG Zhi-hong, WANG Jia-li, et al   

  1. Lab center for preventive medicine, Fujian medical University,Fuzhou 350004, China
  • Received:2004-02-19 Revised:2004-06-30 Online:2004-11-30 Published:2004-11-30
  • Contact: CHEN Hua

PDF (PC)

2607

Abstract: BACKGROUND ＆ AIM: To study the antioxidative and antitumor effcts of Curcuma longa L decoction on H22 tumorigenic mouse. MATERIAL AND METHODS: The H22 tumorigenic mice were oral administrated with the decoction with 24 g /kg, 12 g/kg and 6 g/kg curcuma longa L respectively for 8 days. Weight of tumor, both GSH and SOD activities of animal blood were determined. RESULTS： Inhibition of tumor growth was found for curcuma longa L decoction. But curcuma longa L decoction could significantly increase the levels of GSH and SOD on H22 tumorigenic mice blood. CONCLUTION： In this investigation, Curcuma longa L decoction has no obvious antitumor effect, but has antioxidative effect on H22 tumorigenic mice.

Key words: Curcuma longa L, H22, antitumor, antioxiditant