Ames实验对叶黄素的致突变性与抗突变性研究

doi:10.3969/j.issn.1004-616x.2006.01.019

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2006, Vol. 18 ›› Issue (1): 65-067.doi: 10.3969/j.issn.1004-616x.2006.01.019

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Studies on the Safety and Antimutagenicity of Lutein

WANG Ming-chen1; ZHANG Shan-feng1;MAO Hong-li2;JIN Guo-ping1;DONG Zi-ming1

1.Department of Biochemistry and Molecular Biology,Medical College, Zhengzhou University, Zhengzhou 450052, China; 2.The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052,Henan,China

Received:2005-04-22 Revised:2005-09-02 Online:2006-01-30 Published:2006-01-30
Contact: WANG Ming-chen1

Abstract

Abstract: BACKGROUND ＆ AIM: To study the effects of lutein on mutagenicity and antimutation anti-mutagenicity. MATERIAL AND METHODS: The studies were conducted with Ames test. RESULTS: In Ames test, the mutagenicity of Lutein group was no more than 2 times that of the control group. In test, comparing with positive group, Lutein groups could decrease the colonies in TA98 and TA100 strains. CONCLUSION: No mutagenicity was observed with lutein in this study .Moreover, we demonstrated that lutein possessed significant antimutagenic properties.

Key words: Lutein, Ames test, anti-mutagenicity

CLC Number:

R114

WANG Ming-chen, ZHANG Shan-feng, MAO Hong-li, JIN Guo-ping, DONG Zi-ming. Studies on the Safety and Antimutagenicity of Lutein[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2006, 18(1): 65-067.

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Studies on the Safety and Antimutagenicity of Lutein

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