Carcinogenesis, Teratogenesis & Mutagenesis ›› 1998, Vol. 10 ›› Issue (6): 359-360.doi: 10.3969/j.issn.1004-616x.1998.06.008

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EXPERIMENTAL RESEARCHON EFFECTOF ALLITRADI ON IMPROVING GJIC AND ANTI2OXIDATION

Luo yang ,Wu Gengshu , Zhang Liyan ,et al   

  1. S henyang Medical College , S henyang , 110031
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-11-30 Published:1998-11-30

Abstract: The effect of allit radi on improving GJ IC and anti2oxidation was investigated by measuring oxygen f ree radicals , GJ IC(gap junction intercellular communication) and DNA. The result s showed that allit radi could prevent the cytotoxicity by anti2oxidation , relieve the inhibition of phenobarbitone on GJ IC( P < 0101) . It implys that allit radi could prevent the effect of phenobarbitone on promoting carcinogenesis by increasing the GJ IC function , and inhibit the toxic effect of oxygen f ree radicals on hepatocytes.

Key words: Allit radi, phenobarbitone, GJIC, oxygen f ree radicals