ZHANG Ya-li,SUN Yu-tao,WENG Deng-po,XU Li-hong. The effects of tributyltin on PP2A activity in mouse spleens, livers and brains[J]. Carcinogenesis, Teratogenesis & Mutagenesis, doi: 10.3969/j.issn.1004-616x.2013.03.007.
[1] Graceli JB,Sena GC,Lopes PF,et al. Organotins:a review of their reproductive toxicity,biochemistry,and environmental fate [J]. Reprod Toxicol,2012,36 (1) :40-52. [2] Gupta M,Dwivedi UN,Khandelwal S. C-Phycocyanin:An effective protective agent against thymic atrophy by tributyltin [J]. Toxicol Lett,2011,204 (1):2-11.[3] Dudimah FD,Griffey D,Wang X,et al. Activation of p44/42 MAPK plays a role in the TBT-induced loss of human natural killer (NK) cell function[J]. Cell Biol Toxicol,2010,26 (5): 435-444.[4] Ishihara Y,Kawami T,Ishida A,et al. Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione S-transferase in rat organotypic hippocampal slice cultures [J]. Neurochem Int,2012,60 (8):782-790. [5] Nakatsu Y,Kotake Y,Takai N,et al. Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death[J]. J Toxicol Sci, 2010,35 (2):245-251.[6] Zuo Z,Chen S,Wu T,et al. Tributyltin causes obesity and hepatic steatosis in male mice[J]. Environ Toxicol,2011,26 (1):79-85.[7] Grondin M,Marion M,Denizeau F,et al. Tributyltin induces apoptotic signaling in hepatocytes through pathways involving the endoplasmic reticulum and mitochondria[J]. Toxicol Appl Pharmacol,2007,222 (1):57-68. [8] Liu HG,Wang Y,Lian L,et al. Tributyltin induces DNA damage as well as oxidative damage in rats [J]. Environ Toxicol,2006, 21 (2):166-171.[9] Liu H,Guo Z,Xu L,et al. Protective effect of green tea polyphenols on tributyltin-induced oxidative damage detected by in vivo and in vitro models [J]. Environ Toxicol,2008,23 (1): 77-83.[10] Liu HG,Xu LH. Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro[J]. J Food Prot,2007,70 (3): 716-721.[11] Zhang Y,Liang J,Sun L,et al. Inhibition of PP2A and the consequent activation of JNK/c-Jun are involved in tributyltin-induced apoptosis in human amnionic cells[J]. Environ Toxicol, 2011. doi:10.1002/tox.20730. [12] Zhang Y,Chen Y,Liang J,et al. Protein phosphatases 2A as well as reactive oxygen species involved in tributyltin-induced apoptosis in mouse livers[J]. Environ Toxicol,2012. doi: 10.1002/tox.21751.[13] Chen L,Liu L,Huang S. Cadmium activates the mitogen activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5[J]. Free Radic Biol Med,2008,45 (7):1035-1044.[14] Chen L,Liu L,Yin J,et al. Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5,leading to activation of MAPK pathway[J]. Int J Biochem Cell Biol,2009,41 (6):1284-1295.[15] Kalev P,Simicek M,Vazquez I,et al. Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition[J]. Cancer Res,2012,72 (24):6414-6424. [16] Yoon SY,Choi JE,Choi JM,et al. Dynein cleavage and microtubule accumulation in okadaic acid-treated neurons[J]. Neurosci Lett,2008,437 (2):111-115.[17] Tar K,Csortos C,Czikora I,et al. Role of protein phosphatase 2A in the regulation of endothelial cell cytoskeleton structure [J]. J Cell Biochem,2006,98 (4):931-953.[18] Janssens V,Rebollo A. The role and therapeutic potential of Ser/Thr phosphatase PP2A in apoptotic signalling networks in human cancer cells [J]. Curr Mol Med,2012,12 (3):268-287.[19] Deng X,Gao F,May WS. Protein phosphatase 2A inactivates Bcl2's antiapoptotic function by dephosphorylation and up-regulation of Bcl-2-p53 binding[J]. Blood ,2009,113 (2): 422-428.[20] Boyer IJ. Toxicity of dibutyltin,tributyltin and other organotin compounds to humans and to experimental animals[J]. Toxicology, 1989,55 (3):253–298. [21] Gennari A,Viviani B,Galli CL,et al. Organotins induce apoptosis by disturbance of [Ca (2+)] (i) and mitochondrial activity,causing oxidative stress and activation of caspases in rat thymocytes[J]. Toxicol Appl Pharmacol,2000,169 (2): 185-190.[22] Bissonnette SL,Haas A,Mann KK,et al. The role of CaMKII in calcium-activated death pathways in bone marrow B cells[J]. Toxicol Sci,2010,118 (1):108-118.[23] Tada-Oikawa S,Kato T,Kuribayashi K,et al. Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis[J]. Biochem Pharmacol, 2008,75 (2):552-561.[24] Trotta R,Ciarlariello D,Dal Col J,et al. The PP2A inhibitor SET regulates natural killer cell IFN-gamma production[J]. J Exp Med,2007,204 (10):2397-2405.[25] Howe CJ,LaHair MM,McCubrey JA,et al. Redox regulation of the calcium/calmodulin-dependent protein kinases[J]. J Biol Chem,2004,279 (43):44573-44581.[26] Nakatsu Y,Kotake Y,Komasaka K,et al. Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons [J]. Toxicol Sci,2006,89 (1): 235-242.[27] Nakatsu Y,Kotake Y,Hino A,et al. Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death [J]. Toxicol Appl Pharmacol,2008,230 (3):358-363.[28] Wu Y,Song P,Xu J,et al. Activation of protein phosphatase 2A by palmitate inhibits AMP-activated protein kinase[J]. J Biol Chem,2007,282 (13):9777-9788.