[1] Zhang L,Meng X,Ju X,et al. One-carbon metabolism pathway gene variants and risk of clear cell renal cell carcinoma in a Chinese population[J]. PloS One,2013,8(11):81129. [2] Anderson OS,Sant KE,Dolinoy DC. Nutrition and epigenetics:an interplay of dietary methyl donors,one-carbon metabolism and DNA methylation[J]. J Nutr Biochem,2012,23(8):853-859. [3] Ambros V. MicroRNA pathways in flies and worms:growth,death, fat,stress and timing[J]. Cell,2003,113(6):673-676. [4] Lema C,Cunningham MJ. MicroRNAs and their implications in toxicological research[J]. Toxicol Lett,2010,198(2):100-105. [5] 冯先武,刘青杰. microRNA 作为电离辐射生物标志物的研究现状[J]. 癌变·畸变·突变,2012,24(5):389-392. [6] Du T,Zamore PD. Microprimer:the biogenesis and function of microRNA[J]. Development,2005,132(21):4645-4652. [7] Kozomara A,Griffiths-Jones S. miRBase:annotating high confidence microRNAs using deep sequencing data[J]. Nucleic Acids Res,2014, 42:68-73. [8] Sayed D,Abdellatif M. MicroRNAs in development and disease[J]. Physiol Rev,2011,91(3):827-887. [9] Bartel DP. MicroRNAs:target recognition and regulatory functions[J]. Cell,2009,136(2):215-233. [10] Alvarez-Garcia I,Miska EA. MicroRNA functions in animal development and human disease[J]. Development,2005,132(21): 4653-4662. [11] Liang Y,Li Y,Li Z,et al. Mechanism of folate deficiency-induced apoptosis in mouse embryonic stem cells:Cell cycle arrest/apoptosis in G1/G0 mediated by microRNA-302a and tumor suppressor gene Lats2[J]. Int J Biochem Cell Biol,2012,44(11):1750-1760. [12] Cordes KR,Sheehy NT,White MP,et al. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity[J]. Nature,2009, 460(7256):705-710. [13] Kato M,Slack FJ. microRNAs:small molecules with big roles-C. elegans to human cancer[J]. Biol Cell,2008,100(2):71-81. [14] 关雅萍,王 俊,王宝成. MicroRNA:一种新型的肺癌诊断,预测和治疗的生物标志物[J]. 中国肿瘤生物治疗杂志,2013,4:26. [15] Marsit CJ,Eddy K,Kelsey KT. MicroRNA responses to cellular stress[J]. Cancer Res,2006,66(22):10843-10848. [16] Mishra PJ,Humeniuk R,Mishra PJ,et al. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance[J]. Proc Natl Acad Sci,2007,104(33): 13513-13518. [17] Shookhoff JM,Gallicano GI. A new perspective on neural tube defects:folic acid and microRNA misexpression[J]. genesis,2010, 48(5):282-294. [18] Welch C,Chen Y,Stallings RL. MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells[J]. Oncogene,2007,26(34):5017-5022. [19] Humbert PO,Verona R,Trimarchi JM,et al. E2f3 is critical for normal cellular proliferation[J]. Gene Dev,2000,14(6):690-703. [20] Mathers JC. Reversal of DNA hypomethylation by folic acid supplements:possible role in colorectal cancer prevention[J]. Gut, 2005,54(5):579-581. [21] Stone N,Pangilinan F,Molloy AM,et al. Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes[J]. PLoS One,2011,6(7):e21851. [22] Wu C,Gong Y,Sun A,et al. The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding[J]. Nutr Metab Cardiovas,2013,23(7):693-698. [23] Bolusani S,Young BA,Cole NA,et al. Mammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues[J]. J Biol Chem,2011,286(7): 5166-5174. [24] Selcuklu SD,Donoghue MTA,Rehmet K,et al. MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells[J]. J Biol Chem, 2012,287(35):29516-29528. [25] Minguzzi S,Selcuklu SD,Spillane C,et al. An NTD-associated polymorphism in the 3'UTR of MTHFD1L can affect disease risk by altering miRNA binding[J]. Hum Mutat,2014,35(1):96-104. [26] Zhao JY,Qiao B,Duan WY,et al. Genetic variants reducing MTR gene expression increase the risk of congenital heart disease in Han Chinese populations[J]. Eur Heart J,2014,35(11):733-742. [27] Shimoji K,Kimura T,Kondo A,et al. Genetic studies of myelomeningocele[J]. Child Nerv Syst,2013,29(9):1417-1425. [28] Kaur U,Chakrabarti SS,Pandey BL. MicroRNAs and cardiovascular medicine[J]. SAGE Open Medicine,2014,doi:10.117712050312114 524952. |