Carcinogenesis, Teratogenesis & Mutagenesis ›› 2003, Vol. 15 ›› Issue (2): 104-106.doi: 10.3969/j.issn.1004-616x.2003.02.013

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EFFECT OF As2O3 ON THE RATE OF MICRONULEUS OF VICIA FABA ROOT TIP CELLS AND REPRODUCTION QUANTITY OF FRUIT FLY

ZHONG Xiao-zhi1, QIAN Xiao-wei2   

  1. 1. Department of Pathogen Biology and Immunology, Xiushan Campus, Wenzhou Medical College, Wenzhou 325003, China; 2. Department of Biology and Environmental Science, Wenzhou Normal College, Wenzhou 325003, China
  • Received:2003-01-03 Revised:2003-02-10 Online:2003-04-30 Published:2003-04-30
  • Contact: ZHONG Xiao-zhi

Abstract: Purpose: In this study Vicia faba root tip and fruit flies were used as experimental subjects, effects of different concentrations of As2O3 on the micronuleus frequency of vicia faba root tip cells and reproduction quantity of fruit flies were studied. Methods: The micronuleus test of vicia faba root tip cells and culture of fruit flies were performed. Results: The different concentrations of As2O3 can induce high frequency of micronucleus and increase reproduction quantity of fruit flies. Conclusion: The results showed that As2O3 has cytogenetic toxic effect on the root tip cells of Vicia faba, and has accelerating effect of reproduction quantity of fruit flies.

Key words: arsenic trioxide, micronucleus frequency, reproduction quantity of fruit flies