内质网应激反应IRE1α信号通路与细胞衰老在癌症中的作用及关系的研究进展

doi:10.3969/j.issn.1004-616x.2021.01.015

[1] HAMPTON R Y. ER stress response:Getting the UPR hand on misfolded proteins[J]. Curr Biol, 2000, 10(14):R518-R521.
[2] HERNANDEZSEGURA A, NEHME J, DEMARIA M. Hallmarks of cellular senescence[J]. Trends Cell Biol, 2018, 28(6):436-453.
[3] MATOS L, GOUVEIA A M, ALMEIDA H. ER stress response in human cellular models of senescence[J]. J Gerontol Ser A:Biol Sci Med Sci, 2015, 70(8):924-935.
[4] CHEVET E, HETZ C, SAMALI A. Endoplasmic reticulum stressactivated cell reprogramming in oncogenesis[J]. Cancer Discov, 2015, 5(6):586-597.
[5] WANG M, KAUFMAN R J. The impact of the endoplasmic reticulum protein-folding environment on cancer development[J]. Nat Rev Cancer, 2014, 14(9):581-597.
[6] FRAKES A E, DILLIN A. The UPRER:sensor and coordinator of organismal homeostasis[J]. Mol Cell, 2017, 66(6):761-771.
[7] WU Y, SHAN B, DAI J, et al. Dual role for inositol-requiring enzyme 1α in promoting the development of hepatocellular carcinoma during diet-induced obesity in mice[J]. Hepatology, 2018, 68(2):533-546.
[8] MALHI H, KAUFMAN R J. Endoplasmic reticulum stress in liver disease[J]. J Hepatol, 2011, 54(4):795-809.
[9] CHEN X, ILIOPOULOS D, ZHANG Q, et al. XBP₁ promotes triplenegative breast cancer by controlling the HIF1α pathway[J]. Nature, 2014, 508(7494):103-107.
[10] ZHAO N, CAO J, XU L, et al. Pharmacological targeting of MYCregulated IRE1/XBP₁ pathway suppresses MYC-driven breast cancer[J]. J Clin Invest, 2018, 128(4):1283-1299.
[11] SHENG X, ARNOLDUSSEN Y J, STORM M, et al. Divergent androgen regulation of unfolded protein response pathways drives prostate cancer[J]. EMBO Mol Med, 2015, 7(6):788-801.
[12] SHENG X, NENSETH H Z, QU S, et al. IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling[J]. Nat Commun, 2019, 10(1):323.
[13] ZHANG T, LI N, SUN C, et al. MYC and the unfolded protein response in cancer:synthetic lethal partners in crime?[J]. EMBO Mol Med, 2020, 12(5):e11845.
[14] SONG M, SANDOVAL T A, CHAE C S, et al. IRE1α-XBP₁ controls T cell function in ovarian cancer by regulating mitochondrial activity[J]. Nature, 2018, 562(7727):423-428.
[15] CUBILLOSRUIZ J R, SILBERMAN P C, RUTKOWSKI M R, et al. ER stress sensor XBP₁ controls anti-tumor immunity by disrupting dendritic cell homeostasis[J]. Cell, 2015, 161(7):1527-1538.
[16] ZHANG G H, KAI J Y, CHEN M M, et al. Downregulation of XBP₁ decreases serous ovarian cancer cell viability and enhances sensitivity to oxidative stress by increasing intracellular ROS levels[J]. Oncol Lett, 2019, 18(4):4194-4202.
[17] CUBILLOS-RUIZ J R, BETTIGOLE S E, GLIMCHER L H. Tumorigenic and immunosuppressive effects of endoplasmic Reticulum stress in cancer[J]. Cell, 2017, 168(4):692-706.
[18] CAMPISI J. Aging, cellular senescence, and cancer[J]. Annu Rev Physiol, 2013, 75(1):685-705.
[19] LIU D, HORNSBY P J. Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion[J]. Cancer Res, 2007, 67(7):3117-3126.
[20] LABERGE R M, AWAD P, CAMPISI J, et al. Epithelial-mesenchymal transition induced by senescent fibroblasts[J]. Cancer Microenviron, 2012, 5(1):39-44.
[21] ACOSTA J C, O'LOGHLEN A, BANITO A, et al. Chemokine signaling via the CXCR2 receptor reinforces senescence[J]. Cell, 2008, 133(6):1006-1018.
[22] BANSAL R, NIKIFOROV M A. Pathways of oncogene-induced senescence in human melanocytic cells[J]. Cell Cycle, 2010, 9(14):2854-2860.
[23] DENOYELLE C, ABOURJAILY G, BEZROOKOVE V, et al. Antioncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway[J]. Nat Cell Biol, 2006, 8(10):10531063.
[24] ZHU B K, FERRY C H, MARKELL L K, et al. The nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) promotes on cogene-induced cellular senescence through repression of endoplasmic reticulum stress[J]. J Biol Chem, 2014, 289(29):20102-20119.
[25] BLAZANIN N, SON J, CRAIG-LUCAS A B, et al. ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras[J]. PNAS, 2017, 114(37):9900-9905.
[26] FANG J, YAN Y, TENG X, et al. Melatonin prevents senescence of canine adiposederived mesenchymal stem cells through activating NRF₂ and inhibiting ER stress[J]. Aging (Albany NY), 2018, 10(10):2954-2972.
[27] CHOI S I, LEE E, AKUZUM B, et al. Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation[J]. J Pineal Res, 2017, 63(3):e12426.
[28] KAPETA S, CHONDROGIANNI N, GONOS E S. Nuclear erythroid factor 2mediated proteasome activation delays senescence in human fibroblasts[J]. J Biol Chem, 2010, 285(11):8171-8184.
[29] SONG Y, SHEN H, DU W, et al. Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages[J]. Aging Cell, 2013, 12(5):794-801.
[30] CASSETTA L, POLLARD J W. Targeting macrophages:therapeutic approaches in cancer[J]. Nat Rev Drug Discov, 2018, 17(12):887-904.

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	WANG Miao, WANG Quankai, LI Xinwei, MA Shunpeng, WUHAN Baolier, XU Jianning. m⁶A methylation of mRNAs in glycidyl methacrylate-induced malignant transformation of 16HBE cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(6): 405-409.
[2]	GAO Xiaobin, WU Xueliang, WANG Shengjie, SUN Guangyuan, WANG Wenjing, LIANG Feng, ZHAO Yifeng, LIU Zhenxian, ZHANG Yingchun. Expression of TRIM59 and its correlations with clinicopathological features in colorectal cancers [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(6): 446-450.
[3]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(6): 470-474.
[4]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(6): 475-481.
[5]	CUI Zhaoyang, LI Suna, JIANG Xuqian, WANG Yidan, HOU Liying. Activation of the TRAIL death receptor by apigenin for induction of apoptosis in the gastric cancer SGC-7901 cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(1): 32-36.
[6]	LI Jinglei, HOU Wei. ceRNA network-based stigmasterolintervention on lung squamous cell carcinoma [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(6): 423-429.
[7]	SHI Hailin, HE Tianji, LIU Feng, CAI Menghui, GE Bo. Prognostic value of TCGA-database mutation burden in muscle-invasive bladder cancers [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(6): 430-437,443.
[8]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(6): 477-480,484.
[9]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(6): 485-489.
[10]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(4): 317-320,324.
[11]	LUAN Yiran, LIU Liyuan, JIAO Long, WANG Yueling, BAI Hanyu, ZOU Naiyi, MA Ming. Clinical significance of miR-429 and Bmi-1 mRNA expression in diffuse large B-cell lymphoma [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(3): 177-181.
[12]	GULZARIA·Aikula, TAN Yao, PALIDA·Apiziaji. Expression of long non-coding RNAs in esophageal squamous cell carcinoma of Kazak nationality in Xinjiang [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(3): 194-197,202.
[13]	SHU Zhixiong, WU Chuancheng, WU Xiaoli, LIU Baoying. Relationships between gastric cancer and SNPs of autophagy-related genes on the PI3K/Akt/mTOR pathway [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(2): 118-125,131.
[14]	. [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2020, 32(1): 67-71.
[15]	MA Xiaobiao, ZHANG Qi, PAN Dingguo. Association between rs4143815 polymorphism in the B7-H1 gene and risk of colorectal cancer [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(6): 440-443,448.