吲哚-3-乙酸对人外周血淋巴细胞微核和SCE频率的影响

doi:10.3969/j.issn.1004-616x.2004.03.013

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (3): 171-172.doi: 10.3969/j.issn.1004-616x.2004.03.013

Previous Articles Next Articles

The Effect of the Indole-3-Acetic Acid on the SCE and Micronuclei of Human Peripheral Lymphocytes

HU Xiao-yan, HUANG Chen, SONG Tu-sheng, et al

The Medical School of Xi'an Jiaotong University, Xi'an 710061,China

Received:2003-06-23 Revised:2003-09-01 Online:2004-05-30 Published:2004-05-30
Contact: HU Xiao-yan

Abstract

Abstract: BACKGROUND ＆ AIM： To study the effect of the indole-3-acetic acid(IAA)on the SCE and micronuclei of human peripheral lymphocytes. MATERIAL AND METHODS: We apply IAA to detect micronuclei and SCE of human peripheral lymphocytes. RESULTS： There were salience difference on the micronuclei rate and SCE rate between each group treated with different concentration of the indole-3-acetic acid and the negative controlled group（P<0.05）. CONCLUSION: The indole-3-acetic acid damaged the genetic material of human peripheral lymphocytes.

Key words: Indole-3-acetic acid, SCE, micronuclei

HU Xiao-yan, HUANG Chen, SONG Tu-sheng, et al. The Effect of the Indole-3-Acetic Acid on the SCE and Micronuclei of Human Peripheral Lymphocytes[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2004, 16(3): 171-172.

[1]	LIANG Feng, ZHANG Wei, LI Fei, WANG Shengjie, DU Yujing, ZHANG Yingchun. Expressions of lncRNA CASC9 in colorectal cancer and its relationship with clinical prognosis [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2022, 34(2): 110-113.
[2]	JIANG Shan, DU Feng, KANG Bingwen, YIN Caocao, ZHOU Jian, SHI Ying, WANG Yue, ZHOU Gengyao, QIN Xujun. Attenuation of D-galactose-induced senescence of human umbilical vein endothelial cells by isorhamnetin [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2021, 33(2): 95-100.
[3]	TANG Jiao, YANG Ying, LI Qing, ZHAO Min, YANG Yingfen. In vitro induction of micronuclei by Panax notoginseng extracting solution [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(5): 397-400.
[4]	YAO Jia, LIU Xing, LU Guangyu, ZHU Fangyu, WU Qianqian, LI Xiangming. Screening of chemical mutagens based on RNR3 romoter-regulated red-green fluorescent protein dual signals in yeast cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(4): 276-282.
[5]	YING Wei, WANG Xingyuan, JIANG Bo, ZHOU Wei. Association between polymorphisms in the miR-146a and susceptibility to non-small cell lung cancer [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2019, 31(3): 222-226.
[6]	YANG Shaoyi, ZHANG Qingying, WU Jundong, LIN Qiuqiang, WANG Ruifeng, ZHENG Qingyuan, CAI Fen. Genetic variations in the mitotic checkpoint gene MAD1L1, and risk for breast cancer [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2018, 30(3): 209-213.
[7]	LI Penghao, QU Ting, HUANG Jihua, HAN Tingting, WEN Zina, CUI Shuyan, ZHONG Ying. A refined technique for fluorescence in situ hybridization with human oocyte chromosomes [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(2): 131-133,140.
[8]	YU Decai, MIAO Long, YANG Wenwen, ZHANG Juan, YIN Lihong, PU Yuepu. Association between GJB2 genetic polymorphisms and occupational hearing loss in Chinese Han population [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(2): 121-124,130.
[9]	WU Qingsong, FU Zhongxue. Association between polymorphisms of XRCC1 Arg194Trp and susceptibility to colorectal cancer in Chinese: a Meta-analysis [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2016, 28(2): 134-140.
[10]	YANG Shaozhe, SHI Haijun, CHU Xinran, ZHOU Xiaoling, SUN Pingnan. A simple and high throughput screening method for GFP reporter assay in cells [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2015, 27(5): 394-398,403.
[11]	HUANG Zheng-jie，JIANG Long，YOU Jun，ZENG Yue-yue，WU Bing-lin，CHEN Bai-sheng，FENG Qing-zhao，LUO Qi. Expression and the clinicopathological significance of SOX2 in gastric cancer [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2014, 26(2): 104-107.
[12]	CHEN Jian-ling，LI Wen-xue，DONG Zhi-ning，CHEN Wen，ZHU Wei. Development of TRFIA kit for quantitative analysis of fumonisin B1 [J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2013, 25(1): 48-52.
[13]	TANG Yong-fei;ZHAN Na;HUANG Ya-bing;LIU Lin. Clinicopathological implication of HER-2/neu protein expression and gene amplication in esophageal carcinoma [J]. , 2012, 24(4): 256-260.
[14]	LIAO Jing，LIU Ai-lin，CAO Wen-cheng，LU Wen-qing. Genotoxicity detection of trihalomethanes and haloaceto-nitriles using cytokinesis-block micronucleus test [J]. , 2012, 24(1): 42-45.
[15]	LI Xin，CHEN Mei-fen，CHEN Xiu-juan，XIONG Xi-kun，LI Qing，WANG Feng-yan. Safety assessment of Sauropus androgynus L. Merr. in vitro [J]. , 2011, 23(3): 222-225.

The Effect of the Indole-3-Acetic Acid on the SCE and Micronuclei of Human Peripheral Lymphocytes

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments