沿淮河某市自来水有机提取物对小鼠的诱变性研究

doi:10.3969/j.issn.1004-616x.2002.02.013

癌变·畸变·突变 ›› 2002, Vol. 14 ›› Issue (2): 112-114.doi: 10.3969/j.issn.1004-616x.2002.02.013

沿淮河某市自来水有机提取物对小鼠的诱变性研究

江城梅1;庄　颖1;田　磊2

1. 蚌埠医学院卫生学教研室,安徽　蚌埠　233003; 2. 蚌埠市卫生防疫站食品卫生科,安徽　蚌埠　233000

收稿日期:2001-05-23 修回日期:2001-07-18 出版日期:2002-04-30 发布日期:2002-04-30
通讯作者: 江城梅

MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE

JIANG Cheng－mei1;ZUANG Ying1;TIAN Lei2

1. Department of Public Health, Bengbu Medical College, Bengbu 233003, China; 2. Bengbu City Sani-tation and Anti-epidemic Station, Bengbu 233000, China

Received:2001-05-23 Revised:2001-07-18 Online:2002-04-30 Published:2002-04-30
Contact: JIANG Cheng-mei

摘要/Abstract

摘要： 目的:探讨某市自来水有机提取物对小鼠的诱变性。方法:采集淮河水源水、自来水厂滤池出水、氯化消毒自来水及大型贮水箱水各200 L 。经吸附,提取有机物后予小鼠灌胃染毒,检测胸骨骨髓嗜多染红细胞微核率和精子畸形率,并作U 检验。结果:淮河水源水及氯化消毒的自来水均有一定的致突变性。毒性大小依次为氯化消毒的自来水> 贮水箱水> 水源水> 滤池出水。结论:淮河水源水已受到有机诱变物的污染,混凝沉淀具有去除有机物、降低源水诱变性作用,而氯化消毒使水质的诱变性增高。

关键词: 水污染, 有机提取物, 诱变性, 小鼠

Abstract: Purpose : To explore the mutagenicity of organic ext ract s of tap water in a certain city in mice. Methods : Each 200 L of water was collected separately from Huai river source water , water of clarifying filt ration , chlorinated tap water and reservoir’s water. After being adsorbed and concent rated , water samples were poured into mouse stomaches. Micronucleus frequency in mouse thoracic bone-marrow polychromatic erythrocyte ( PCE) and sperm deformity rate were determined. Results : Mutagenicity of some degree were determined from Huai river source water and chlorinated tap water. The order of mutagenic intensity was as follows ; chlorinated tap water > reservoir’s water > source water > water of clarifying filteration. Conclusions : The source water was contaminated by organic mutagens. After coagulation and precipitation , mutagenicity of source water decreased because some mutagenic organic chemicals could be removed. While chlorination increased mutagenicity of tap water.

Key words: water pollution, organic extract, mutagenicity, mouse

中图分类号:

R123. 3

江城梅, 庄　颖, 田　磊. 沿淮河某市自来水有机提取物对小鼠的诱变性研究[J]. 癌变·畸变·突变, 2002, 14(2): 112-114.

JIANG Cheng－mei, ZUANG Ying, TIAN Lei. MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2002, 14(2): 112-114.

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沿淮河某市自来水有机提取物对小鼠的诱变性研究

MUTAGENICITY OF ORGANIC EXTRACTS OF TAP WATER IN A CERTAIN CITY IN MICE

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