关键词: 微核试验, 致突变, 微核率, 污染指数, 化学需氧量

Abstract: OBJECTIVE： To examine the association between the degree of pollution of the water around residential Kunming and mutagenicity. METHODS：The micronucleus test of Vicia faba root tip cell was used to detect the water quality，and to survey the chemical oxygen demand(CODcr).The micronuclear rates and Pollution Index(PI) were determined and the F-test was used to evaluate the difference in micronuclear rates among different samples. RESULTS: There was significant difference in micronuclear rates of every site(P<0.01). PI values of 7 among 9 sampling sites were over 2.00. The micronuclear rates were higher in the sites with higher PI. There was no obvious pattern in the results of CODcr. CONCLUSION：The degree of pollution was directly related to the level of mutagenicity.But the water mutagenic activity was not directly related to the chemical oxygen demand.

Key words: micronucleus test, mutagenicity, micronuclear rates, pollution index, chemical oxygen demand