癌变·畸变·突变 ›› 2003, Vol. 15 ›› Issue (2): 104-106.doi: 10.3969/j.issn.1004-616x.2003.02.013

• 论文 • 上一篇    下一篇

三氧化二砷(As2O3)对蚕豆根尖微核率和果蝇发生量的影响

钟晓芝1, 钱晓薇2   

  1. 1.温州医学院绣山校区免疫学和病原生物学教研室, 浙江 温州 325003; 2.温州师范学院生物与环境科学系,浙江  温州 325003
  • 收稿日期:2003-01-03 修回日期:2003-02-10 出版日期:2003-04-30 发布日期:2003-04-30
  • 通讯作者: 钟晓芝

EFFECT OF As2O3 ON THE RATE OF MICRONULEUS OF VICIA FABA ROOT TIP CELLS AND REPRODUCTION QUANTITY OF FRUIT FLY

ZHONG Xiao-zhi1, QIAN Xiao-wei2   

  1. 1. Department of Pathogen Biology and Immunology, Xiushan Campus, Wenzhou Medical College, Wenzhou 325003, China; 2. Department of Biology and Environmental Science, Wenzhou Normal College, Wenzhou 325003, China
  • Received:2003-01-03 Revised:2003-02-10 Online:2003-04-30 Published:2003-04-30
  • Contact: ZHONG Xiao-zhi

摘要: 目的: 研究不同浓度As2O3对蚕豆胚根根尖微核率和果蝇发生量的影响作用。 方法: 以蚕豆根尖和果蝇为实验对象,均用不同浓度As2O3处理,采用蚕豆胚根根尖微核实验和果蝇培养实验。 结果: 不同浓度As2O3可使蚕豆根尖细胞微核率和果蝇发生量明显上升。 结论: 三氧化二砷(As2O3)对蚕豆根尖具有明显的毒性效应;在一定条件下,对果蝇发生量有促进作用。

关键词: As2O3, 微核率, 果蝇发生量

Abstract: Purpose: In this study Vicia faba root tip and fruit flies were used as experimental subjects, effects of different concentrations of As2O3 on the micronuleus frequency of vicia faba root tip cells and reproduction quantity of fruit flies were studied. Methods: The micronuleus test of vicia faba root tip cells and culture of fruit flies were performed. Results: The different concentrations of As2O3 can induce high frequency of micronucleus and increase reproduction quantity of fruit flies. Conclusion: The results showed that As2O3 has cytogenetic toxic effect on the root tip cells of Vicia faba, and has accelerating effect of reproduction quantity of fruit flies.

Key words: arsenic trioxide, micronucleus frequency, reproduction quantity of fruit flies