关键词: 合成色素, 遗传毒理学, 生物学检测

Abstract: This article is about the study on genetical toxical effect s of five home2made edible synthetic pigments by suing bioassay. Result s showed that the synthetic pigment s with certain dose range would evidently induce the increase of micronucleus frequencies of Tradescantia Pal udosa tet rads , The micronucleus frequencies reached significant or highly significant difference as compared with cont rol ( P < 0. 05 , P < 0. 01) , There was also the obvious dose2response relationshop. F test also showed that significant difference of tet rad micronucleus frequencies induced by five pigment s. Meanwhile they could induce the increase of micronucleus f requencies of Vicia f aba root2tip cells , the test indicated an ultimate difference between higher dose groups and the cont rol group. The study suggested that the edible synthetic pigment s could induce chromosomes damage in plant sex cells and somatic cells , and that had genetical toxical effect s with tested dose.

Key words: Synthetic pigment s, Genetical toxiity, Bioassay