癌变·畸变·突变 ›› 2004, Vol. 16 ›› Issue (3): 181-182.doi: 10.3969/j.issn.1004-616x.2004.03.017

• 肿瘤防治 • 上一篇    下一篇

乳腺癌患者及其家族成员血清TSGF的检测

李明烈   

  1. 上海市肿瘤研究所，　上海　200032
  • 收稿日期:2004-01-04 修回日期:2004-02-16 出版日期:2004-05-30 发布日期:2004-05-30
  • 通讯作者: 李明烈

Determination of Serum TSGF in Patients with Breast Carcinoma and Their Familial Members

LI Ming-lie   

  1. Shanghai Cancer Institute, Shanghai 200032,China
  • Received:2004-01-04 Revised:2004-02-16 Online:2004-05-30 Published:2004-05-30
  • Contact: LI Ming-lie

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摘要： 背景与目的：评估乳腺癌患者(BC)及其家族成员(FM)血清肿瘤特异性生长因子(TSGF)水平的变化。材料与方法： 应用生化比色法检测30例乳腺癌患者和30例家族成员血清TSGF水平。结果：30例BC患者血清TSGF水平(78.5±13.4)高于正常健康人(NS)(48.8±6.2)；FM组的TSGF水平(69.6±9.9)亦高于NS组。结论：血清TSGF的检测可作为乳腺癌及其易患个体的诊断和筛选的指标。

关键词: 肿瘤特异性生长因子, 乳腺癌, 家族成员

Abstract: BACKGROUND ＆ AIM : To evaluate the changes of the serum TSGF (tumor specific growth factor) in patients with breast carcinoma(BC) and their familial members(FM).MATERIAL AND METHODS : The changes of serum TSGF in the 30 cases with BC and 30 FM were determined using spectrophotometry method. RESULTS: The serum level of TSGF in patients with BC(78.5±13.4),compared with normal subjects (NS)(48.8±6.2), were significantly increased(P<0.01).There also were statistical differences in serum level between FM(69.6±9.9) and the NS(P<0.01). CONCLUSION: It is suggested that changes of TSGF may serve as an indicator of diagnosis for BC and their susceptible individuals.

Key words: tumor specific growth factor, breast carcinoma, familial member

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