Abstract: To understand the mechanism of mutagenesis inhibitory effect of Turmeric oil , the authors designed a series of testing procedures to examine the inhibitory effect by Turmeric oil on the mutagenesis induced by Mitomycine (MMC) in Escherichia Coil lysogenic st rain of GY5027 as indicated by GY4015 as following ways : A.GY5027 was added after Turmeric oil and MMC had been put together for 20 minutes. B. Turmeric oil was added after GY5027 had been t reated with MMC for 20 minutes. C. MMC was added after GY5027 had been treated with Turmeric oil for 20 minutes. D. GY5027 , Turmeric oil and MMC were put into together at the same time. Result s found that in all of the above A , B , C and D experimental designs , the mutagnesis was significantly inhibited by Turmeric oil. This indicates that Turmeric oil might be able to inhibit mutagenesis both intercellularly and ext racellularly and repair genetic damages caused by genotoxicant .

Key words: Turmeric oil, Antimutagenesis, Mechanism