Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (2): 78-080.doi: 10.3969/j.issn.1004-616x.1999.02.005
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Tang Yingxia , Yu Kang , Shen Zhijian , Hu Xiaoxia , Wang Xiaotong
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Abstract: To study the f requency of ApoB、ApoE alleles in population of Southern Zhejiang , we collected 60 random healthy individuals to detect the polymorphic sites EcoR Ⅰ、Xba Ⅰof ApoB. Hha Ⅰof ApoE by PCR-RFL Ps. The result showed X- allele and E+ allele of Xba Ⅰand EcoR Ⅰ rest riction sites of ApoB have an advantage in f requencies of alleles having relative f requency of 0. 983 and 0. 967 , respectively. X+ and E- alleles were very rare. The f requencies of the three ApoE alleles were E2 = 0. 02 , E3 = 0. 86 , E4 = 0. 12.
Key words: Apoliporotein B, Apolipoprotein E, Frequencies of alleles, Polymerase chain reaction
Tang Yingxia , Yu Kang , Shen Zhijian , Hu Xiaoxia , Wang Xiaotong. THE FREQUENCY OF APOLIPOPROTEIN B, E ALLELES IN SOUTHERN ZHEJAING[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 1999, 11(2): 78-080.
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