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doi:10.3969/j.issn.1004-616x.2003.03.003

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2003, Vol. 15 ›› Issue (3): 138-140.doi: 10.3969/j.issn.1004-616x.2003.03.003

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STUDIES OF PREVENTIVE EFFECT ON HYDROXY FREE RADICAL－INDUCED CHL CELLULAR DNA DAMAGE BY SPIRULINA PLATENSIS

GE Hua－bing1, SUN Zheng1, LIU Hong－yan2, et al

1.Faculty of Stomatology, Capital University of Medical Sciences, Beijing 100050，China;2.Institute of Materia Medica Chinese Academy of medicine Sciences and Peking Union Medical College, Beijing 100050,China

Received:2002-12-23 Revised:2003-05-16 Online:2003-07-30 Published:2003-07-30
Contact: SUN Zheng

Abstract

Abstract: Purpose: The aim of this study was to observe the anti－oxidative activity of spirulina platensis and to explore anticarciogenic mechanism of spirulina platensis. Methods: Single cell gel electrophoresis (SCGE) assay was used to observe and evaluate the anti－oxidative activity of spirulina platensis. Results: T he results demonstrated that Spirulina platensis could protect CHL cellular DNA from damage induced by hydroxy free radical in dose－dependent manner. Conclusion： The anti－oxidative activity of spirulina platensis might plays an important role in cancer chemoprevention.

Key words: spirulina platensis, hydroxy free radical, DNA injury, anti－oxidition, single cell gel electrophoresis

GE Hua－bing, SUN Zheng, LIU Hong－yan, et al. STUDIES OF PREVENTIVE EFFECT ON HYDROXY FREE RADICAL－INDUCED CHL CELLULAR DNA DAMAGE BY SPIRULINA PLATENSIS[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2003, 15(3): 138-140.

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STUDIES OF PREVENTIVE EFFECT ON HYDROXY FREE RADICAL－INDUCED CHL CELLULAR DNA DAMAGE BY SPIRULINA PLATENSIS

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