Carcinogenesis, Teratogenesis & Mutagenesis ›› 2000, Vol. 12 ›› Issue (4): 218-220.doi: 10.3969/j.issn.1004-616x.2000.04.007

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IM MUNOCYTOCHEMISTRY STUDY OF B7．1 IN SIX TUMOR CELL LINES

CHEN Mei—zhen ，SI Hua—xin ，SI Lu sheng，et al   

  1. Department of Pathology，Medical Collage shantou Uni~erslty．Shontou 515031,China;2.Institute of lmmunopathology，Xi’an Medical University，Xi’an 710061，China
  • Received:2000-01-02 Revised:2000-06-20 Online:2000-10-30 Published:2000-10-30

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Abstract: purpose：To observe the expression of costimuLatory mo|ecule B7 1 in tumor cell 1ines and establish the cel1 modelto studvthe function 0{B7．1 n vitro．M ethods：B7．1 molecule Of tumor cd11ines was studied by SABC immunocytochemistry．staining Results：An cell liaes(7721，BLS211．GRC1，MGC)except BLZ211 and A375 expre．~sed B7．1．Conclusion：M o．st of the tumor cd1 fines studied in this experiment have no ddideacy in expre~slon of B7 1 protein The B7．1 poMtive eell 1ines can he used as models to study 137．1 function in vitro

Key words: tumor cell 1ines, B7 1, immunocytochemistry

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