Carcinogenesis, Teratogenesis & Mutagenesis ›› 2005, Vol. 17 ›› Issue (1): 56-58.doi: 10.3969/j.issn.1004-616x.2005.01.019

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Study of Toxicity of Juice of Cactus

CHENG Dong;HAN Xiao-ying;FENG Ning;et al   

  1. Department of Toxicology, Shandong Center for Disease Prevention and Control，Jinan 250014, China
  • Received:2004-04-14 Revised:2004-06-20 Online:2005-01-30 Published:2005-01-30
  • Contact: CHENG Dong

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Abstract: BACKGROUND ＆ AIM: To study the toxicity of juice of cactus. MATERIAL AND METHODS: Acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice,sperm shape abnormality test of mice,thirty days feeding study. RESULTS: Juice of cactus had no toxicity according to the acute toxicity (LD50>20.0 g/kg).The results of genetic toxicity test were all negative,including Ames test,micronucleus test and sperm shape abnormality test.The results of thirty days feeding study was also negative. CONCLUSION: Juice of cactus had no toxicity and had no genetic toxicity and subacute toxicity in this test. 　　

Key words: juice of cactus, acute toxicity test, genetic toxicity test, thirty days feeding study