一起放射性伤害事故受照者1.5年后染色体畸变随访观察

doi:10.3969/j.issn.1004-616x.2005.06.019

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2005, Vol. 17 ›› Issue (6): 386-388.doi: 10.3969/j.issn.1004-616x.2005.06.019

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A Follow-up Study on Chromosomal Aberrations in the Victim of Radiation Injury Accident After 1.5 Years

CHEN Ying; SUN Ou-jun; LUO Yi-sheng; LIU Xiu-lin

Institute of Radiation Medicine, Academy of Military Medical Sciences

Received:2004-11-29 Revised:2005-03-15 Online:2005-11-30 Published:2005-11-30
Contact: CHEN Ying

Abstract

Abstract: BACKGROUND & ATM: To follow late effects of a victim in a radiation injury accident and observe cytogenetic characteristics of a continual irradiation. MATERIAL AND METHODS: Conventional chromosomal aberrations and G-banded kayrotype analysis. RESULTS: There are little decline in dicentrics. Stable aberrations such as translocations play dominant role in total aberration frequency of 26 %. Clonal aberrations are not yet observed. CONCLUTION: There are more severe cytogenetic damage and slower repair in continual exposure to radiation than in single irradiation.

Key words: continual exposure, chromosomal aberrations, translocation, late radiation effect

CHEN Ying, SUN Ou-jun, LUO Yi-sheng, LIU Xiu-lin. A Follow-up Study on Chromosomal Aberrations in the Victim of Radiation Injury Accident After 1.5 Years[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2005, 17(6): 386-388.

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A Follow-up Study on Chromosomal Aberrations in the Victim of Radiation Injury Accident After 1.5 Years

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