复方消经痛胶囊致突变性研究

doi:10.3969/j.issn.1004-616x.2010.01.016

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2010, Vol. 22 ›› Issue (1): 62-0064.doi: 10.3969/j.issn.1004-616x.2010.01.016

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Study on mutagenicity of fufang xiaojingtong capsules

LI Lan-fang1;TONG Ji-ming2;XIE Li-jun1;LI Guo-feng1;HAO Na1;ZHANG Qin-zeng1;WANG Wei1

1.Hebei Provincial Cent for Disease Control and Prevention，Shijiazhuang 050021, Hebei;2.Chengde Medical College, Chengde 067000, Hebei, China

Received:2009-07-03 Revised:2009-10-10 Online:2010-01-30 Published:2010-01-30
Contact: LI Lan-fang

Abstract

Abstract: OBJECTIVE: To study the mutagenicity of Fufang Xiaojingtong capsules (FFXC). METHODS: The mouse sperm morphology test , the mouse sperm chromosomal aberration test and the mouse bone marrow micronucleus test were used to evaluate mutagenicity of FFXC. RESULTS: The results of sperm morphology rates, the sperm chromosomal aberration test and the bone marrow micronucleus rates were negative. CONCLUSION: FFXC had no mutagenic effects in our study.

Key words: Fufang Xiaojingtong capsule, mutagenicity, sperm abnormality test, sperm chromosomal aberration test, micronucleus test

CLC Number:

R711.51

LI Lan-fang, TONG Ji-ming, XIE Li-jun, LI Guo-feng, HAO Na, ZHANG Qin-zeng, WANG Wei. Study on mutagenicity of fufang xiaojingtong capsules[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(1): 62-0064.

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Study on mutagenicity of fufang xiaojingtong capsules

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