关键词: 杜仲, 急性毒性, 遗传毒性

Abstract: BACKGROUND ＆ AIM： Although Duzhong was listed on the function food roll, there was lack of data of systematic toxic/safety evaluation experiments. MATERIAL AND METHODS： Safety evaluation experiment was done using acute toxicity experiment, cell toxicity experiment and genetic toxicity experiment . RESULTS： CHL and CHO were 109.38 mg/ml;it was negative in toxicity. CONCLUSION: It was found that Du zhong was a non-toxic substance and was negative in genetic toxicity,although it had some toxic effect on the CHO and CHL cell at higher dose levels.

Key words: Duzhong, acute toxicity, genetic toxicity