大连地区母血和脐血铊浓度及其相关的影响因素

doi:10.3969/j.issn.1004-616x.2010.02.010

癌变·畸变·突变 ›› 2010, Vol. 22 ›› Issue (2): 119-122.doi: 10.3969/j.issn.1004-616x.2010.02.010

大连地区母血和脐血铊浓度及其相关的影响因素

邵小翠1;朴丰源1;关怀1;2;李小薇2;徐蕾3;横山和仁3

1. 大连医科大学劳动与环境卫生教研室，辽宁大连 116044 ； 2. 解放军第210医院妇产科，辽宁大连 116021；3. 三重大学医学部，津市日本

收稿日期:2009-09-09 修回日期:2009-11-13 出版日期:2010-03-30 发布日期:2010-03-30
通讯作者: 朴丰源

Blood thallium levels of maternal and umbilical cord blood and the related factors in Dalian

SHAO Xiao-cui1;PIAO Feng-yuan1;GUAN Huai1;2;LI Xiao-wei2;XU Lei3;Yokoyama Kazuhito3

(1. Department of Occupational and Environmental Health, Dalian Medical University,Dalian 116044; 2. Department of Obstetrics and Gynecology, No.210 Hospital of PLA, Dalian 116021, China; 3. Department of Public Health and Occupational Medicine, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu-shi,Mie 514-8507, Japan

Received:2009-09-09 Revised:2009-11-13 Online:2010-03-30 Published:2010-03-30
Contact: PIAO Feng-yuan

摘要/Abstract

摘要： 目的：检测分析大连地区母血和脐血中铊浓度及其相关影响因素，为孕期合理保健提供资料。方法：收集125对母血及脐血，采用电感耦合等离子体-质谱(ICP-MS)法测定其血中铊的浓度，同时就孕妇家庭和社会环境等因素对血铊浓度的影响进行单因素分析和多元线性回归分析。结果：大连地区母血和脐血中铊的浓度分别为48.8±29.9 ng/L和 42.0±29.2 ng/L，两者间的差异具有统计学意义(P<0.05),且母血和脐血的铊浓度之间呈正相关(r=0.731)。母血铊浓度因居住地和饮水来源、有无被动吸烟、有无妊娠并发症、是否近期家庭装修等因素的不同而存在差异；多元线性回归分析结果显示，其中饮水来源、有无被动吸烟和有无妊娠并发症等3个因素进入回归方程。结论：大连地区孕妇及其胎儿均受到铊暴露，居住地、妊娠并发证、被动吸烟、饮水来源、家庭装修等因素均影响母血铊浓度。

关键词: 铊, 影响因素, 母血, 脐血

Abstract: OBJECTIVE: To examine thallium levels of maternal and umbilical cord blood, and analyze some relevant influencing factors. METHODS: We selected 125 pregnant women. Their venous bloods were drawn and subject to the microwave digestion method. The concentration of blood thallium was determined by ICP-MS. The effects of the relevant factors, including family condition and social environment of each pregnant woman, on the concentration of blood thallium were analyzed. The average thallium levels of maternal and umbilical cord blood were 48.8±29.9 ng/L and 42.0±29.2 ng/L, respectively, the correlation coefficient was 0.731. Several factors were found to be related to the thallium concentration of maternal blood, such as place of residence, source of drinking water, passive smoking, home renovation(P<0.05). The results of multiple linear regression analysis of the relevant influencing factors were source of drinking water, passive smoking, complications of pregnancy. CONCLUSION:Place of residence, passive smoking, source of drinking water, home renovation were the factors affecting the thallium level of maternal blood (P<0.05).

Key words: thallium, influence factors, cord blood, maternal blood

中图分类号:

R135.1

邵小翠, 朴丰源, 关怀, 李小薇, 徐蕾, 横山和仁. 大连地区母血和脐血铊浓度及其相关的影响因素[J]. 癌变·畸变·突变, 2010, 22(2): 119-122.

SHAO Xiao-cui, PIAO Feng-yuan, GUAN Huai, LI Xiao-wei, XU Lei, Yokoyama Kazuhito. Blood thallium levels of maternal and umbilical cord blood and the related factors in Dalian[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(2): 119-122.

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大连地区母血和脐血铊浓度及其相关的影响因素

Blood thallium levels of maternal and umbilical cord blood and the related factors in Dalian

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