CA125、CA199、CEA和AFP检测在卵巢肿瘤诊断中的价值

doi:10.3969/j.issn.1004-616x.2010.04.017

癌变·畸变·突变 ›› 2010, Vol. 22 ›› Issue (4): 315-316.doi: 10.3969/j.issn.1004-616x.2010.04.017

CA125、CA199、CEA和AFP检测在卵巢肿瘤诊断中的价值

高郁森

惠州市中心人民医院妇产科, 广东惠州 516001

收稿日期:2010-04-16 修回日期:2010-06-04 出版日期:2010-07-30 发布日期:2010-07-30
通讯作者: 高郁森

Diagnostic value of determination of serum CA125, CA199,CEA and AFP in patients with ovarian tumors

GAO Yu-sen

Department of Gynaecology and Obstetrics, Huizhou Central People's Hospital, Huizhou 516001,Guangdong, China

Received:2010-04-16 Revised:2010-06-04 Online:2010-07-30 Published:2010-07-30
Contact: GAO Yu-sen

摘要/Abstract

摘要： 目的: 探讨血清CA125、CA199、癌胚抗原(CEA)和甲胎蛋白(AFP)的检测在卵巢肿瘤诊断中的价值。方法: 采用化学发光法检测卵巢恶性肿瘤、良性肿瘤患者血清CA125、CA199、CEA及AFP水平。结果: 卵巢恶性肿瘤患者血清CA125、CA199水平明显高于卵巢良性肿瘤患者(P<0.01)，CEA和AFP值在卵巢恶性肿瘤与卵巢良性肿瘤患者间的差异无统计学意义(P>0.05)。结论: CA125、CA199 的检测有助于对卵巢恶性肿瘤诊断, 而CEA及AFP的检测对卵巢恶性肿瘤的诊断无明显价值。

关键词: 卵巢肿瘤, 癌抗原125, 糖链抗原199, 癌胚抗原, 甲胎蛋白

Abstract: OBJECTIVE: To study the diagnostic value of the cancer antigen 125(CA125), cancer antigen 199 (CA199)，CEA and AFP in patients with ovarian tumors. METHODS: RIA was used to measure the levels of serum CA125, CA199，CEA and AFP in patients with benign and malignant ovarian tumors. RESULTS: Serum CA125 and CA199 levels were significantly higher in the patients with malignant ovarian tumor than those with benign ovarian tumor(P<0.01), The differences of CEA and AFP levels between benign and malignant ovarian tumors were not significant(P>0.05). CONCLUSION: The single detection of CA125 and CA199 may be the best method for diagnosing ovarian tumors, and the detection of AFP and CEA has no value for diagnosing ovarian tumors.

Key words: ovarian tumors, cancer antigen 125, carbohydrate antigen 199, carcinoembryonic antigen, alpha- fetoprotein

中图分类号:

R737.31

高郁森. CA125、CA199、CEA和AFP检测在卵巢肿瘤诊断中的价值[J]. 癌变·畸变·突变, 2010, 22(4): 315-316.

GAO Yu-sen. Diagnostic value of determination of serum CA125, CA199,CEA and AFP in patients with ovarian tumors[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(4): 315-316.

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CA125、CA199、CEA和AFP检测在卵巢肿瘤诊断中的价值

Diagnostic value of determination of serum CA125, CA199,CEA and AFP in patients with ovarian tumors

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