福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究

doi:10.3969/j.issn.1004-616x.2010.06.010

癌变·畸变·突变 ›› 2010, Vol. 22 ›› Issue (6): 452-454.doi: 10.3969/j.issn.1004-616x.2010.06.010

福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究

郑能雄，徐幽琼，王春兰，林华影，柯　华，林　侃，肖明发

福州市疾病预防控制中心，福建福州 350004

收稿日期:2010-05-20 修回日期:2010-07-20 出版日期:2010-11-30 发布日期:2010-11-30

In vivo genetic toxicity of organic extractions from drinking and source water in Fuzhou

ZHENG Neng_xiong, XU You-qiong, WANG Chun-lan, LIN Hua-ying, KE Hua, LIN Kan, XIAO Ming-fa

Fuzhou Center for Disease Control and Prevention, Fuzhou 350004,Fujian, China

Received:2010-05-20 Revised:2010-07-20 Online:2010-11-30 Published:2010-11-30

摘要/Abstract

摘要： 目的：探讨福州市生活饮用水及其水源水的体内遗传毒性。方法：随机选择福州市5个区县(市)各1家水厂，采集水源水和出厂水各200 L，经XAD_2树脂柱收集其中的有机物，采用小鼠骨髓细胞微核试验和精子畸形试验检测其遗传毒性。结果：长乐市、平潭县水厂出厂水和水源水及福清市水厂出厂水具有致突变性；各出厂水有机提取物的致突变性基本高于同厂水源水。结论：福州市部分生活饮用水水源水和出厂水受到一定程度的有机物污染。

关键词: 生活饮用水, 有机提取物, 体内遗传毒性

Abstract: OBJECTIVE: To evaluate the in vivo genotoxicity of drinking and source water in Fuzhou. METHODS: Five districts were randomly chosen in Fuzhou with a water plant in every district. 200 liters drinking water and source water were sampled in every district. XAD_2 resin was used to extract the organic matter in water, and mouse bone marrow micronucleus and sperm abnormality test were used to detect the genotoxicity of the organic extractions. RESULTS: The drinking and source water of water plants in Changle city and Pingtan county and the drinking water of water plant in Fuqing city were mutagenic, and the genotoxicity of organic extractions of drinking water was higher than that of its source water. CONCLUSION: The drinking and source water of Fuzhou city had been polluted by organic compounds to some degree.

Key words: drinking water, organic extractions, in vivo genotoxicity

郑能雄, 徐幽琼, 王春兰, 林华影, 柯　华, 林　侃, 肖明发. 福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究[J]. 癌变·畸变·突变, 2010, 22(6): 452-454.

ZHENG Neng_xiong, XU You-qiong, WANG Chun-lan, LIN Hua-ying, KE Hua, LIN Kan, XIAO Ming-fa. In vivo genetic toxicity of organic extractions from drinking and source water in Fuzhou[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2010, 22(6): 452-454.

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福州市生活饮用水及其水源水有机提取物的体内遗传毒性研究

In vivo genetic toxicity of organic extractions from drinking and source water in Fuzhou

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