癌变·畸变·突变 ›› 2005, Vol. 17 ›› Issue (6): 357-359.doi: 10.3969/j.issn.1004-616x.2005.06.010

• 论著 • 上一篇    下一篇

食管癌高低发区饮用水微量元素谱的多元分析

盘 鹰;何小英   

  1. 汕头大学医学院化学教研室
  • 收稿日期:2004-09-09 修回日期:2005-05-27 出版日期:2005-11-30 发布日期:2005-11-30
  • 通讯作者: 盘 鹰

Multivariate Analysis on Spectra of Trace Elements in Tap Water in Areas with High and Low Incidence of Esophageal Cancer

PAN Ying, HE Xiao-ying   

  1. Department of Chemistry, Medical College of Shantou University
  • Received:2004-09-09 Revised:2005-05-27 Online:2005-11-30 Published:2005-11-30
  • Contact: PAN Ying

摘要: 背景与目的: 研究食管癌高低发区饮用水中微量元素谱(Trace elements,TE),为食管癌(Esophageal cancer,EC)病因提供研究依据。材料与方法:采集食管癌高低发地区的饮用水样,用高频电感耦合等离子体发射光谱法(Inductively coupled plasma_atomic emission spectgrometry,ICP_AES)测定13种元素(Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Se, Sr, V, Zn)含量,并进行t检验、相关分析、建立回归方程。 结果: 检测发现食管癌高低发区的水样中的微量元素谱不同,Fisher判别法,其识别准确率为93%。 结论: 不同环境水中微量元素对食管癌发生率有影响。

关键词: 微量元素, 判别分析, 食管癌,

Abstract: BACKGROUND &AIM: To study the spectra of trace elements (TE) in tap water to provide the research basis of pathogenesis of esophageal cancer (EC). MATERIAL AND METHODS: Thirteen trace elements (Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Se, Sr, V, Zn) in tap water of different districts were studied. The contents of TE were analyzed with t_test and correlation analysis and the regression equation was established. RESULTS: The TE spectra of TE in tap water in areas with high and low incidences of EC were discriminated using Fisher method, the accuracy rates were up the 93%.CONCLUSION: The TE in water of different districts could affect the incidence of EC.

Key words: trace element, discrimination analysis, esophageal cancer, tap water