癌变·畸变·突变 ›› 2000, Vol. 12 ›› Issue (2): 87-089.doi: 10.3969/j.issn.1004-616x.2000.02.008

• 论著 • 上一篇    下一篇

22 种可食性中药材的抗突变和致突变同步快速试验报告

赵泽贞,魏丽珍   

  1. 河北省肿瘤研究所,河北 石家庄 050011
  • 收稿日期:1999-06-15 修回日期:1999-09-30 出版日期:2000-04-30 发布日期:2000-04-30

THE REPORT ON THE MUTAGENICITY AND ANTIMUTAGENICITY SYNCHRONOUS TEST OF A LOT OF EDIBLE CHINESE HERB

ZHAO Ze - zhen , WEI Li - Zhen   

  1. Hebei Cancer Instit ute , S hijiaz huang  050011 , China
  • Received:1999-06-15 Revised:1999-09-30 Online:2000-04-30 Published:2000-04-30

摘要: 目的与方法:为筛选有抗突变作用的物质,采用抗突变和致突变同步快速试验对蜂蜜、蜂王浆、蜂采花粉、百合、海带、柳芽、薏米仁、槐豆、蘑芋、桂圆、胖大海、车前叶、白菊花、山药、芫荽、榆叶、南瓜籽、南瓜肉、冬瓜肉、冬瓜皮、佛手瓜、菱角22 种可食性中药材进行了试验。结果与结论:经加和不加大鼠肝脏微粒体酶(S9) 两种试验,结果全部受试物均未发现致突变毒性;蜂蜜、蜂王浆、蜂采花粉、柳芽、槐豆、桂圆、白菊花、山药及菱角9 种显示对丝裂霉素C 引起的致突变作用有拮抗效应。

关键词: 可食性中药材, 抗突变, 致突变, 同步试验

Abstract: Purpose and Methods : In order to screening the antimutagen , the study investigated the mutagenicity and antimutagenicity of 22 kinds of edible chinese herb(Honey , Royal jelly , Bee collecting pollen , Lily , Kely ,Willow bud , the seed of Job’s tear , the Pob of chinese scholort ree , Olired longan , Taro , Sterulaia scaphi , Asiatic plantain , White chrysanthemum , Chinese yam , Coriander , Elm leaf , Pumpkin seeds , Pumpkin pulp , pulp of wagourd , Skin of wagourd Fingered cit ron , Water chestunt by the antimutagenicity and mutagenicity synchronous test . Results and Conclusion : The result s both with and without S9 (rat liver microsomal enzymes) showed that all the samples had no mutagenicity. Honey , Royal jelly , Bee Collecting Pollen , Willow Bud , the pob of chinese scholort ree , Olired longan , White chrysantemum , Chinese yam , Water chestunt were antimutagen against MMC.

Key words: Edible Chinse herb, antimutagenicity, mutagenicity, synchronous test

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