DNA 合成抑制实验检测烹调油烟对人羊膜成纤维细胞WISH 的致突变性研究

doi:10.3969/j.issn.1004-616x.2000.02.016

癌变·畸变·突变 ›› 2000, Vol. 12 ›› Issue (2): 111-112.doi: 10.3969/j.issn.1004-616x.2000.02.016

DNA 合成抑制实验检测烹调油烟对人羊膜成纤维细胞WISH 的致突变性研究

蒋东霞1 , 胡杰英1 , 杨胜利2

11 河南省肿瘤研究所,河南郑州　450003 ; 21 河南医科大学,河南郑州　450052

收稿日期:1999-07-27 修回日期:1999-11-30 出版日期:2000-04-30 发布日期:2000-04-30

THE EFFECT OF COOKING OIL CONDENSATE ON DNA SYNTHESIS INHIBITION IN HUMAN AMINO CELLS WISH

JIANG Dong-xia1 , HU Jie-jing1 , YANG Sheng-li2

1. Henan Tumor Instit ute , Zhengz hou 450003 , China ; 2. Henan Medical University , Zhengzhou 450052 ,China

Received:1999-07-27 Revised:1999-11-30 Online:2000-04-30 Published:2000-04-30

摘要/Abstract

摘要： 目的与方法:本文应用DNA 合成抑制(DSI) 实验对居民家庭烹调油烟进行了致突变性研究。结果:实验结果表明,不同浓度的烹调油烟凝聚物均可见到DNA 合成抑制,具有明显的剂量—效应关系。结论:实验证实,烹调油烟中存在着引发人体细胞DNA 损伤的遗传毒性物质。

关键词: DNA 含成抑制(DSI) 实验, 烹调油烟, 人羊膜成纤维细胞WISH

Abstract: Purpose and Methods :DNA synthesis inhibition (DSI) test was used to study the effect of cooking oil condensate on human amino cells WISH. Results : The result showed that DNA synthesis inhibition rates (DSIR) of cooking oil condensate at 100μg/ ml and 200μg/ ml were 45. 8 % and 85. 8 % respectively , and 0 % at 0. 0μg/ ml in cont rol group. The statistical analysis showed that P value is small than 0. 05. Conclusion : The above2memtioned result s indicated that there were the component s to induce DNA synthesis inhibition in the cooking oil condensate.

Key words: DNA synthesis inhibition (DSI) test, cooking oil condensate, human amino cells WISH

中图分类号:

Q75
Q730. 23

蒋东霞, 胡杰英, 杨胜利. DNA 合成抑制实验检测烹调油烟对人羊膜成纤维细胞WISH 的致突变性研究[J]. 癌变·畸变·突变, 2000, 12(2): 111-112.

JIANG Dong-xia , HU Jie-jing , YANG Sheng-li. THE EFFECT OF COOKING OIL CONDENSATE ON DNA SYNTHESIS INHIBITION IN HUMAN AMINO CELLS WISH[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2000, 12(2): 111-112.

DNA 合成抑制实验检测烹调油烟对人羊膜成纤维细胞WISH 的致突变性研究

THE EFFECT OF COOKING OIL CONDENSATE ON DNA SYNTHESIS INHIBITION IN HUMAN AMINO CELLS WISH

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics

本文评价