癌变·畸变·突变 ›› 2004, Vol. 16 ›› Issue (4): 244-246.doi: 10.3969/j.issn.1004-616x.2004.04.019

• 肿瘤防治 • 上一篇    下一篇

宫颈癌根治术中卵巢移位的价值

李从铸, 翟玉霞, 黄 萍, 周 莉, 李 燕   

  1. 汕头大学医学院附属肿瘤医院妇瘤科, 广东, 汕头 515031
  • 收稿日期:2004-02-07 修回日期:2004-05-20 出版日期:2004-07-30 发布日期:2004-07-30
  • 通讯作者: 李从铸

Evaluation of Transposed Ovaries in Cervical Cancer Patients After Surgery and Pelvic Irradiation

LI Cong-zhu, ZHAI Yu-xia, HUANG-Ping, et al   

  1. Department of Gynecologic Oncology,Tumor Hospital of Shantou University Medical College,Shantou 515031, China
  • Received:2004-02-07 Revised:2004-05-20 Online:2004-07-30 Published:2004-07-30
  • Contact: LI Cong-zhu

摘要: 背景与目的: 探讨宫颈癌根治术中卵巢移位的价值。材料与方法:对75例45岁以下Ia2~IIb早期宫颈鳞癌患者于根治术中行单侧或双侧卵巢移位,通过血清性激素水平测定和超声检测等方法评估移位术后卵巢功能。结果: 卵巢移位术安全可靠,单侧或双侧卵巢移位后均无移位卵巢发生癌转移现象;移位后未辅加放疗组卵巢功能无明显变化,辅加放疗组雌、孕激素水平虽较未放疗组减低,但仍显著高于根治性放疗组。结论: 45岁以下宫颈癌患者根治术中保留卵巢安全有效,可显著提高患者雌、孕激素水平。

关键词: 宫颈癌, 年轻患者, 卵巢移位

Abstract: BACKGROUND & AIM: To evaluate the value of transposed ovaries in cervical cancer patients after surgery and pelvic irradiation. MATERIAL AND METHODS: In 75 patients with stage Ia2~IIb cervical cancer, 24~45 years of age, Wertheim-Meigs radical hysterectomy was performed with preservation of one or both ovaries transposed outside the pelvis. For evaluation of the post-treatment hormonal function of gonads, serum FSH, LH, estradiol and progesterone levels were assayed after irradiation. RESULTS: The method of transposed ovaries is safety and effective. No patients with retained ovaries developed metastatic disease. The patients who postoperative radiotherapy be indicated occur a substantial loss of ovarian function, but the levels of estradiol and progesterone significantly higher than in the radical therapy group. CONCLUSION: It is our opinion that normal ovaries can be preserved in the women under the age of 45 years at the time of radical hysterectomy for stage Ib~IIb cervical cancer.

Key words: cervical cancer, young patient, transposition of ovary