Carcinogenesis, Teratogenesis & Mutagenesis ›› 1998, Vol. 10 ›› Issue (3): 163-167.doi: 10.3969/j.issn.1004-616x.1998.03.010

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THE RESEARCH ON THE FREQUENCES OF MICRONUCLI AND CHROMOSOME BREAKS OF THE DIMETHYLFORMAMIDE AND BUTADIENE EXPOSED WORKERS

Wang Deqi , Ai Xiaoqing , Dong Dinglong , Zhao Guohua , Yu Ming , Zhang J ianhua , Wnag Yong , Zhang Hong   

  1. The Instit ute of Improving Bi rth Quality and Geneties of Daqing Medical College for Staff Members , Daqing 　163312
  • Received:1900-01-01 Revised:1900-01-01 Online:1998-05-30 Published:1998-05-30

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Abstract: To study whether Dimethylformamide and Butadiene can damage the worker’genetic materials , the paper observed 64 Dimethylformamide and Butadiene exposed workers’frequences of micronucli using the micronucleus technique , and chromosome breaks using karyotyping analysis. Dimethylformamide and Butadiene exposed workers’micronucleus rate , micronucleus cell and chromosome breaks rate are 14. 69 ‰、12. 40 ‰、1. 61 % respectively , significantly higher than cont rol group ( P < 0. 01) . The result s showed that Dimethylformamide and Butadiene can damage workers , genetic materials.

Key words: Dimethylformamide, Butadiene, genetic materials