Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (1): 32-034.doi: 10.3969/j.issn.1004-616x.1999.01.011

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STUDY ON THE ANTIMUTAGENICITY OF A - CM MARINE BIOLOGICAL PREPERATION

Zhong Jinyi, Zhang yanbin, Sun Fengyun   

  1. Qingdao Medical College, Qingdao  266021
  • Received:1998-03-20 Revised:1998-06-04 Online:1999-01-30 Published:1999-01-30

Abstract: The antimutagenicity of A - CM marine biological preperation was studied with several genotoxicological test s which included antigenetic reverse mutation test in S almonella typhimurium st rain TA 100 , the test of antimicronucleus effect in vivo mice bone marrow on PCEs induced by common mutagens Cd2 + and NO -2 ,and DNA damage resistance test . Result s consistently demonst rate that A - CM preperation has significant antimutagenic effect on gene mutation and chromosome clastogen in all above tests.

Key words: Antimutagenicity, DNA damage, Marine biological preperation