Carcinogenesis, Teratogenesis & Mutagenesis ›› 1999, Vol. 11 ›› Issue (2): 96-098.doi: 10.3969/j.issn.1004-616x.1999.02.011

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STUDY ON GENETICAL TOXICAL EFFECTS OF FIVE EDIBLE SYNTHETIC PIGMENTS

Lin Jiancheng1 , Lin Suxia2   

  1. 1Biochemist ry Department of Putian Junior College , Fujian Province 351100 , 2 Putian Couty Hospital
  • Received:1998-08-26 Revised:1998-11-21 Online:1999-03-30 Published:1999-03-30

Abstract: This article is about the study on genetical toxical effect s of five home2made edible synthetic pigments by suing bioassay. Result s showed that the synthetic pigment s with certain dose range would evidently induce the increase of micronucleus frequencies of Tradescantia Pal udosa tet rads , The micronucleus frequencies reached significant or highly significant difference as compared with cont rol ( P < 0. 05 , P < 0. 01) , There was also the obvious dose2response relationshop. F test also showed that significant difference of tet rad micronucleus frequencies induced by five pigment s. Meanwhile they could induce the increase of micronucleus f requencies of Vicia f aba root2tip cells , the test indicated an ultimate difference between higher dose groups and the cont rol group. The study suggested that the edible synthetic pigment s could induce chromosomes damage in plant sex cells and somatic cells , and that had genetical toxical effect s with tested dose.

Key words: Synthetic pigment s, Genetical toxiity, Bioassay