成核透明剂ZC-3的急性毒性和遗传毒性试验

doi:10.3969/j.issn.1004-616x.2004.04.015

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (4): 235-236.doi: 10.3969/j.issn.1004-616x.2004.04.015

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Acute Toxicity and Genetic Toxicity Tests of DMDBS

ZHOU Wen, LI Hui, TANG Hui, et al

Department of Toxicology,Shandong Center for Disease Prevention and Control,Jinan 250014,China

Received:2003-11-17 Revised:2004-01-06 Online:2004-07-30 Published:2004-07-30
Contact: ZHOU Wen

Abstract

Abstract: BACKGROUND ＆ AIM: To study the acute toxicity and genetic toxicity of DMDBS. MATERIAL AND METHODS: Acute toxicity test of mice,Ames test,micronucleus test of bone marrow PCE cell in mice, sperm shape abnormality test of mice. RESULTS:DMDBS was a substance with no toxicity according to the acute toxicity. The results of genetic toxicity tests were all negative,including Ames test, micronucleus test and sperm shape abnormality test. CONCLUSION: DMDBS was a substance with no toxicity and had no genetic toxicity in this test.

Key words: enhancement of clarified polypropylene, genetic toxicity, Ames test, micronucleus test, sperm shape abnormality test

ZHOU Wen, LI Hui, TANG Hui, et al. Acute Toxicity and Genetic Toxicity Tests of DMDBS[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2004, 16(4): 235-236.

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Acute Toxicity and Genetic Toxicity Tests of DMDBS

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