Carcinogenesis, Teratogenesis & Mutagenesis ›› 2004, Vol. 16 ›› Issue (6): 352-35.doi: 10.3969/j.issn.1004-616x.2004.06.011

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Genotoxicity Orgenic Pollutants of Chaohu Lake and Effects on Drinking Water Quality

WANG Wei, ZHAO Ying, HUANG Xiao-mu， et al   

  1. Anhui Center for Disease Control and Prevention，Hefei Anhui 230061，China
  • Received:1900-01-01 Revised:1900-01-01 Online:2004-11-30 Published:2004-11-30
  • Contact: WANG Wei

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Abstract: BACKGROUND ＆ AIM： To evaluate the genotoxicity of water organic pollutants of Chaohu Lake and the effects on drinking water quality. MATERIAL AND METHODS： Ames test, micronucleus test and single-cell gel-electrophoresis(SCGE) test were carried out in the water samples from Chaohu Lake water and the finished water plants which use water source from Chaohu Lake. RESULTS: Ames test indicated that the raw water presented suspectable mutagenicity which couldn't be eleminated by coagulation and chlorination. The rates of red cell micronucleus were increased significantly at dose level of 10 μg/g. The result of SCGE showed that the frequencies of comet cells in headwater, unfiltrated water,filtrated water and product water groups were significantly higher than that of negative group. CONCLUSION: The water organic pollutants of Chaohu Lake has potential mutagenicity. We should pay more attention to its genotoxicity and the effects on drinking water quality which related public health.

Key words: Chaohu Lake, organic pollutants, genotoxicity, drinking water