海娜粉染发剂的致突变性研究

doi:10.3969/j.issn.1004-616x.2011.04.015

›› 2011, Vol. 23 ›› Issue (4): 306-307.doi: 10.3969/j.issn.1004-616x.2011.04.015

• 检测研究 • Previous Articles Next Articles

Mutagenic research on hair dyes Henna

TIAN Wei，HUANG Yun-fei，CHEN Yan*，LI Yu-ge

Toxicology Laboratory of Public Health College, Xinjiang Medical University, Urumqi 830011, Xinjiang, China

Received:2010-12-02 Revised:2011-03-31 Online:2011-07-30 Published:2011-07-30
Contact: CHEN Yan

Abstract

Abstract: OBJECTIVE: To assess the mutagenic effects of Henna，which is a special hair dye in Xinjiang. METHODS：Micronucleus test and sperm malformation test were performed to analyze the mutagenicity of Henna. RESULTS：The rates of micronuclei in three Henna groups (with concentrations of 5 000，2 500，1 250 mg/kg，respectively) and control group were 0.8‰，1.0‰，0.9‰ and 0.8‰，respectively. There was no significant difference between Henna groups and control group (P>0. 05). The rates of abnormal sperm in three Henna groups and control group were 1.4%，1.6%，1.4% and 1.3%，respectively. There was no significant difference between Henna groups and control group (P>0. 05). CONCLUSION：Henna showed no mutagenicity under this experimental condition.

Key words: Henna powder, mutagenicity, micronucleus test, sperm abnormality test

TIAN Wei，HUANG Yun-fei，CHEN Yan*，LI Yu-ge. Mutagenic research on hair dyes Henna[J]. , 2011, 23(4): 306-307.

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Mutagenic research on hair dyes Henna

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