Abstract: Aneuploidy in human population is a serious genetic problem. The major cause of this numerical chromosomal aberration is non - disjunction. Some of the common mutagens such as formaldehyde are known to be able to induce non - disjunction. The purpose of this study is to establish a system for the investigation on the mechanism of non - disjunction and identification of the non - disjunction inducing agent s. Tradescantia ref lex a plant which has high spontaneous frequencies of non - disjunction is an ideal system for the study of aneuploidy induction.

Key words: Tradescantia ref lex a, Aneuploidy, Induction