Carcinogenesis, Teratogenesis & Mutagenesis ›› 2007, Vol. 19 ›› Issue (2): 143-146.doi: 10.3969/j.issn.1004-616x.2007.02.018

Previous Articles     Next Articles

Concentrations and Mutagenic Activities of Ambient Particulate Matter and Polycyclic Aromatic Hydrocarbons

PIAO Feng-yuan1, DUAN Zhi-wen2, ZHANG Yu-min2, CUI Jin-shan2, SUN Xian-ce1, YANG Guang1, YAMAUCHI Toru3,   

  1. 1.Department of Hygiene, Dalian Medical University, Dalian 116027, Liaoning, China; 2. Department of Hygiene Toxicology, Faculty of Preventive Medicine, Shenyang Medical College, Shenyang 110034, Liaoning, China; 3. Department of Public Health, Graduate School of Medicine, Mie University, Tsu 514－8507, Mie Prefecture, Japan
  • Received:2006-04-17 Revised:2006-11-13 Online:2007-03-30 Published:2007-03-30
  • Contact: PIAO Feng-yuan

PDF (PC)

2815

Abstract: BACKGROUND ＆ AIM: To investigate concentrations and mutagenic activities of ambient particulate matter (PM) and polycyclic aromatic hydrocarbons(PAHs) in an industrial area of northeastern China. MATERIALS AND METHODS: The concentrations of PM, PAHs and benzo(a)pyrene [B(a)P] were determined by high liquid chromatography (HPLC) and mutagenicity of the samples were examined by the Ames Salmonella mutagenic assay over two years from September 2000 to August 2002 in a northeast industrial city of China. RESULTS: Concentrations of PM, PAHs and BaA were significantly higher in the industrial area than those in the other sampling area(P<0.05 or P<0.01). Mutagenic activities of PM and its extracted organic matters(EOM) were significantly higher in the industrial area than those in the other sampling area(P<0.05 or P<0.01). CONCLUSION: Concentrations of PM and PAHs were high in the industrial area, and there were strong indirect mutagenic activities.

Key words: air pollution, particulate matter (PM), polycyclic aromatic hydrocarbons (PAHs), mutagenic activity, Ames test

CLC Number: