破壁松花粉的毒理试验

doi:10.3969/j.issn.1004-616x.2005.06.017

Carcinogenesis, Teratogenesis & Mutagenesis ›› 2005, Vol. 17 ›› Issue (6): 380-382.doi: 10.3969/j.issn.1004-616x.2005.06.017

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Toxicological Research of Pollen Pini

FAN Bo-lin, TIAN Hui, WANG Hu-min,SONG Yi,FU Shao-hua

Hubei Provincial Center for Disease Control and Prevention, Wuhan 430079,Hubei,China

Received:1900-01-01 Revised:1900-01-01 Online:2005-11-30 Published:2005-11-30
Contact: FAN Bo-lin

Abstract

Abstract: BACKGROUND ＆ AIM: To test the safety of pollen pini as a health food. MATERIAL AND METHODS: Acute toxicity test,bone marrow cell micronucleus test,mice sperm abnormality test and 30 d feeding study were performed to study the toxicity of pollen pini. RESULTS: In acute toxicity test, male and female KM mice were fed with 15 g/kg dose of pollen pini, no toxic symptoms were observed. The results of bone marrow cell micronucleus test and mice sperm abnormality test were negative. In the 30 d feeding test, no obvious toxic effects were detected in clinical examination, blood tests, biochemical tests, organ weights and pathological examination in treated Wistar rats. CONCLUSION: Pollen pini passed the toxicological tests and deemed safe as a kind of health food.

Key words: pollen pini, acute toxicity, micronucleus, sperm abnormality, 30 d feeding test

FAN Bo-lin, TIAN Hui, WANG Hu-min, SONG Yi, FU Shao-hua. Toxicological Research of Pollen Pini[J]. Carcinogenesis, Teratogenesis & Mutagenesis, 2005, 17(6): 380-382.

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Toxicological Research of Pollen Pini

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